• Curriculum Vitae
  • Teaching
  • Appointments
  • Research

• University degree: Biological Sciences, 1983, University of Parma (110/110 cum laude).
• PhD: Molecular Biology and Pathology, 1991, University of Parma.
• 1991 - 2005: Research associate of Biochemistry, University of Parma
• 2005 - to date: Associate Professor of Biochemistry, University of Parma
• At present he coordinates the Section of Veterinary Biochemistry at the Department of Animal Productions, Veterinary Biotechnologies, Food Safety and Quality at the University of Parma.
• Since 1985 Roberto Ramoni has been working on the structure-function relationship in Odorant Binding Proteins (OBP) from mammalian species. In particular he contributed to the resolution of 3D structures of bovine and porcine OBPs and he studied the molecular mechanisms responsible of "domain swapping" in bovine OBP.
• Moreover, he investigated the role of OBP as a carrier/scavenger of toxic molecules produced by peroxidation of unsaturated fatty acids. The study, in particular, was focused on the binding properties and chemical resistance with respect to the alkenaldehyde 4-hydroxy-2-nonenal, that is a compound involved in the pathogenesis of several acute and chronic diseases and cancer.

In the latest years his attention has also been focused on the other following topics:

• A-Preparation and characterization of 'platelet gel' and stem cells to be employed in cell therapy protocols in the field of Veterinary medicine.
• B- Structural and functional characterization of protein involved in in the phage-host interaction in Lactococcus Lactis, a bacterium employed as microbial starter in several diary productions

• He has been involved, as sub-contractor, in a UE funded Scientific Project named OPTIM (BIO4-98-0420) that was focused on the molecular characterization of the odorant and pheromone binding proteins in insects and mammals.
• He has been Scientific Coordinator of MIUR funded project (FIRB) entitled ‘Study on the involvement of human Odorant Binding Protein in the molecular mechanisms that cells oppose to oxidative stress'.
• In 2002 he took part and then coordinated a Research Unit of a PRIN project entitled ‘Characterization a and toxicological role of lipid peroxidation products in different cheese types'.
• In 2008 Dr Ramoni has been funded by the bank Foundation 'Cariparma' for a research project entitled 'preparation of filters based on a protein matrix for the removal from water of atrazine, phtalates and other toxic organic toxic contaminants.
• In 2008 Dr Ramoni has received a grant within the exchange research project between Italy and France named Galileo, for a research entitled 'Structural and functional characterization of the binding complexes between human odorant binding protein and cytotoxic compounds produced during oxidative stress'
• 2011: Coordinator of the bi-lateral research project (three year program) between Italy and Mexico entitled: Resistance to oxidative stress injuries of cells with mitochondria functionalized with a protein scavenger for the removal of 4-hydroxy-2-nonenal. (Mexican coordinator: Dr Diego Gonzalez Halphen, UNAM, Mexico City)

Other research experiences:
• 1988 : Research Assistant at the Institute of Molecular Biology, University of Oregon, Eugene - Prof Sidney Bernhard

Collaborations :
• Dr. Christian Cambillau e Dr. Mariella Tegoni, AFMB-CNRS, Marseille (France) - Characterization of structure-function relationship in native and mutated
• isoforms of mammalian Odorant Binding Proteins. Characterization of the phage-host interaction in Lactococcus lactis.
• Dr. Jean Claude Pernollet, INRA, Jouy en Josas (Francia) - Cloning, etherologous expression and functional characterization of human Odorant Binding Protein (hOBP)
• Prof. Piero Baglioni, CVGI, Università di Firenze. Neutron scatterging of mammalian OBPs
• Dr. Diego Gonzalez Halphen, Instituto de Fisiologia Celular, Univrsidad Nacional Autonoma de Mexico, Mexico City (MEX): OBP targeting to mitochondria
• Prof. Maurizio del Bue, Dipartimento di Salute Animale,Università di Parma: Platlelt gel and stem cell based terapie in Veterinary Medicine
• Dr. Giorgio Giraffa e Dr. Domenico Carminati, CRA-FLC di Lodi: Characterization of phage-host relationship in Lactobacillus Helveticus
• Prof. Claudio Rivetti, Dipartimento di Biochimica e Biologia Molecolare, Università di Parma:
characterizationof DNA binding proteins from Lactococcos Lactis and Lactobacillus helveticus phages by Atomic Force Microscopy

Completion accademic year: 2019/2020

Completion accademic year: 2018/2019

Completion accademic year: 2017/2018

Completion accademic year: 2016/2017

Completion accademic year: 2015/2016

Completion accademic year: 2014/2015

Completion accademic year: 2013/2014

Professor/Teacher

Publications

Contacts

Phone number
902766
Fax number

032772