Personale docente

PERSONAL INFORMATION

Address: Via Falcone e Borsellino, 2 – 26100 Cremona (CR), Italy
Telephone: 0372 561511 (home); 0521 905623 (office); 334 6063228 (mobile)
Fax: 0521 905673
E-mail: massimiliano.zaniboni@unipr.it
Nationality: italian
Date of birth: 13/10/1965
Marital status: Married (2 children)

EDUCATION AND SCIENTIFIC TRAINING

1989: LAUREA DEGREE IN BIOLOGY (University of Parma, IT). 110/110 cum laude
1995: LAUREA DEGREE IN PHYSICS (University of Parma, IT). 110/110 cum laude
1999: PhD IN PHYSIOLOGY (University of Turin, IT)
Sept. 1995 – Nov. 1998: RESEARCH ASSISTANT at the Cardiovascular Research and Training Institute (University of Utah, USA)
Jan. 1999 – Dec. 2001: RESEARCH ASSISTANT at the Physiology Laboratory (University of Oxford, UK).
01 Sept. – 02 Ott. 2002: RESEARCH ASSOCIATE at the New York Medical College (Valhalla, New York, USA)

SCHOOLS AND COURSES

Sept. 1989: School of Mathematical Models in Biology and Medicine. Gargnano sul Garda, Brescia. Italy.
Oct. 1997: International Workshop on Mechano-Electrical Feedback and Cardiac Arrhythmias. Castel Ivano, Trento.

AFFILIATIONS

Since 2001: MEMBER of the Italian Society of Physiology (SIF)
Since 2011: MEMBER of the Italian Society for Cardiovascular Research (SIRC)
Since 09/02/2012: MEMBER of the Center of Excellence for Toxicological Research (CERT) of the University of Parma, Italy
Since 2012: MEMBER of the European Society of Cardiology (ESC)
Since 2012: MEMBER of the European Work Group of Cardiac Cellular Electrophysiology (EWGCCE)

COLLABORATIONS WITH PRIVATE INSTITUTIONS

1991 – 1992: AWARDED BY A SCHOLARSHIP for the project “Improving Glutathione production from yeast”, funded by Biofer S.p.A. (Medolla, MO), Italy.
2003: SCIENTIFIC TUTOR of the Project Spinner 2003 “Anodal stimulation mechanisms in cardiac pacemakers technology”, in collaboration with MEDICO S.p.A. (Padova), Italy.
2003: SCIENTIFIC PARTICIPANT in the Project “Anti-arrhythmic characterization of CHF1024 in the hypertrophic heart”, in collaboration with Chiesi Farmaceutici S.p.A., Parma, Italy..
2008: EXTERNAL CONSULTANT for Chiesi Farmaceutici S.p.A. (Parma, Italy) within the project “An experimental protocol on SA nodal cells from the guinea pig heart: pharmacological modulation of electrophysiological properties”.

PARTICIPATION AND RESPONSIBILITY IN RESEARCH PROJECTS

2001: PARTICIPANT in the Research Program “Myocardial structural and electrical remodelling, autonomic neuropathy and arrhythmias in diabetes, in the presence and absence of cardiac hypertrophy”. PRIN – MIUR
2003: PARTICIPANT in the Research Program “Functional evaluation of regenerative efficacy of stem cells of different origin, in a rat model of myocardial infarction” . PRIN – MIUR
2005: PARTICIPANT in the Research Program “A study of mechanical and electrical competence of the heart regenerated by means of cardiac stem cells, in experimental models of rat myocardial infarction” . PRIN – MIUR
2005: PARTICIPANT in the Research Program “Cell therapy as alternative to organ transplantation: growing and differentiation processes of stem cells towards cardiovascular phenotypes”. FIRB
2005: PARTICIPANT in the Research Program “Rimodellamento morfo-funzionale del tessuto miocardico ventricolare ed efficienza elettro-meccanica del cuore diabetico”. FIL – Università degli Studi di Parma.
2006: SCIENTIFIC RESPONSIBLE for the Research Program “Un nuovo approccio dinamico per lo studio della rate-dependency del potenziale d’azione cardiaco” . FIL – Università degli Studi di Parma.
2007: SCIENTIFIC RESPONSIBLE for the Research Program “Un nuovo approccio dinamico per lo studio della rate-dependency del potenziale d’azione cardiaco” . FIL – Università degli Studi di Parma.
2011-2012: SCIENTIFIC RESPONSIBLE of the Operative Unit UNIPR2 within the PROGETTO DI RICERCA FINALIZZATA 2009 “Integrated approach to evaluate biological effects on lung, cardiovascular system and skin of occupational exposure to nanomaterials (NanoO I-LuCaS)”. MINISTERO DELLA SALUTE – Direzione Generale della Ricerca Scientifica e Tecnologica. Codice RF-2009-1472550.

RESPONSIBILITY IN RESEARCH PROJECTS FUNDED BY PRIVATE INSTITUTIONS

2008: SCIENTIFIC RESPONSIBLE for the Research Project “An experimental protocol on SA nodal cells from the guinea pig heart: pharmacological modulation of electrophysiological properties”. The project has been funded by Chiesi Farmaceutici S.p.A.
2009-2010: SCIENTIFIC RESPONSIBLE for the Research Project “Pharmacological modulation by muscarinic antagonists of electrophysiological properties of guinea pig SA nodal cells”. The project has been funded by Chiesi Farmaceutici S.p.A.
2012: SCIENTIFIC RESPONSIBLE for the Research Project “Pharmacological modulation by muscarinic antagonists of electrophysiological properties of guinea pig SA nodal cells”. The project has been funded by Chiesi Farmaceutici S.p.A.

COLLABORATION WITH INTERNATIONAL JOURNALS

INVITED REVIEWER for the international journals: Annals of Biomedical Engineering, IEEE–Transactions on Biomedical Engineering, Theoretical Biology and Medical Modelling, Mathematical Biosciences.
MEMBER of the Editorial Board of ISRN Physiology.

ORGANIZATION OF EVENTS

MEMBER of the Scientific Board for the 85esimo Convegno Della Società Italiana di Biologia Sperimentale. Parma 29-30 novembre 2012.

TEACHING ACTIVITY

AY 2000/2001: ENVIRONMENTAL PHYSIOLOGY (Corso di Laurea in Scienze Ambientali, Università degli Studi di Parma).
From AY 2001/02 to AY 2005/2006: MOLECULAR PHYSIOLOGY (Corso di Laurea in Biotecnologie, Università degli Studi di Parma).
From AY 2004/2005 to AY 2008/2009: METHODS IN CELL PHYSIOLOGY (Corso di Laurea Specialistica in Biologia e Applicazioni Biomediche e Corso di Laurea Specialistica in Biologia Molecolare, Università degli Studi di Parma).
From AY 2003/2004 to AY 2010/2011: PHYSIOLOGY OF BIOLOGICAL MEMBRANES (Corso di Laurea in Biologia, Università degli Studi di Parma).
AY 2005/2006: ORGAN AND SYSTEMS PHYSIOLOGY (Corso di Laurea in Biotecnologie, Università degli Studi di Parma)
From AY 2006/2007 to AY 2012/2013: GENERAL PHYSIOLOGY (Corso di Laurea in Biotecnologie, Università degli Studi di Parma).
From AY 2011/2012 to AY 2012/2013: MOLECULAR PHYSIOLOGY (Corso di Laurea in Biologia, Università degli Studi di Parma).
AY 2012/2013: PHYSIOLOGY OF EXCITABLE CELLS (Corso di Laurea Specialistica in Biologia Molecolare, Università degli Studi di Parma)

TUTORING IN LAUREA AND DOCTORATE DEGREES

From AY 2001/2002 : MEMBER OF THE TEACHING BOARD for the Corso di Dottorato di Ricerca in Fisiopatologia Sistemica, Università degli Studi di Parma, and Member of the Examination Board of the same Course.
AY 2002/2003: TUTOR FOR THE DOCTORATE THESIS of Francesca Cacciani, within the Corso di Dottorato in Fisiopatologia Cardiovascolare, Università degli Studi di Milano (XV cycle).
AY 2003/2004: TUTOR FOR THE DOCTORATE THESIS of Marcello Rota, within the Corso di Dottorato di Ricerca in Fisiopatologia Sistemica, Università degli Studi di Parma, (XVI cycle).
AY 2006/2007: TUTOR FOR THE DOCTORATE THESIS of Nicolò Salvarani, within the Corso di Dottorato di Ricerca in Fisiopatologia Sistemica, Università degli Studi di Parma, (XIX cycle).
AY 2012/2013: CONTRORELATORE FOR THE DOCTORATE THESIS in Scuola di Dottorato in Bioingegneria (Alma Mater – University of Bologna) (XXV cycle).
From AY 2000/2001: MEMBER OF COMMISSIONE DI LAUREA in Scienze Biologiche, Biotecnologie, Biologia Molecolare, and Biologia e Applicazioni Biomediche.
From AY 2000/2001: TUTOR of more than 40 LAUREA DEGREE dissertations in Scienze Biologiche, Biotecnologie, Biologia Molecolare, Biologia e Applicazioni Biomediche, Fisica and Matematica.

OTHER ACADEMIC RESPONSABILITIES

AY 2007/08: MEMBER OF THE EXAMINING BOARD (Commissione Giudicatrice) for awarding Scholarship (Borsa di Studio) of the University of Parma, Italy.
AY 2009/2010: MEMBER OF THE EXAMINING BOARD (Commissione Giudicatrice) for awarding Scholarship (Borsa di Studio) of the University of Parma, Italy.
AY 2010/2011: MEMBER OF THE EXAMINING BOARD (Commissione Giudicatrice) for awarding Research Fellowship (Assegno di Ricerca) of the University of Parma, Italy.
2006: MEMBER OF THE EXAMINING BOARD (Commissione Giudicatrice) of a National Competition (Concorso Nazionale) for a permanent position as Researcher (Ricercatore a tempo indeterminato) in Physiology (BIO/09) at the University of Pavia, Italy.
2008: MEMBER OF THE EXAMINING BOARD (Commissione Giudicatrice) of a National Competition (Concorso Nazionale) for a permanent position as Researcher (Ricercatore a tempo indeterminato) in Physiology (BIO/09) at the University of Turin, Italy.
Since AY 2011/2012: MEMBER of DIDACTIC COMMITTEE (Commissione Didattica) for the Course of Biology, University of Parma, Italy.

INVITED ORAL PRESENTATIONS

28/06/2000: Arrhythmogenesis in cardiac hypertrophy, an approach from the “in vivo” towards the cellular level. XXVI International Congress on Electrocardiology. Milan, Italy
22/09/2000: Repolarization changes in hypertrophied rat ventricular myocytes paced at different rates. VII Congresso Nazionale della Società Italiana di Ricerche Cardiovascolari (SIRC). Bologna, Italy.
15/03/2002: Meccanismi dell’aritmogenesi nel cuore ipertrofico. Riunione delle Unità Operative del Consorzio Interuniversitario per la Ricerca Cardiovascolare (CIRC). Bologna, Italy.
14(04/2005: How voltage dependency of membrane input resistance affects
DC estimates of membrane capacitance in cardiac myocytes. Invited seminar at the Department of Physiology, University of Bern, Switzerland.
29/03/2007: How voltage dependency of membrane input resistance affects DC estimates of membrane capacitance in cardiac myocytes. Annual Meeting of Gruppo Nazionale per il Calcolo Scientifico (GNCS), dell' Istituto Nazionale di Alta Matematica Francesco Severi (INDAM). Parma, Italy.
25/03/2008: How different can be two identical action potentials. Annual Meeting of Gruppo Nazionale per il Calcolo Scientifico (GNCS), dell' Istituto Nazionale di Alta Matematica Francesco Severi (INDAM).
21/10/2011. Una nuova rappresentazione tridimensionale del potenziale d’azione cardiaco. XVIII Congresso Nazionale Società Italiana Ricerche Cardiovascolari (SIRC). Imola (Bologna), Italy.
30/11/2011: Quanto possono essere diversi due potenziali d’azione identici. Invited seminar at the Istituto di Ingegneria Biomedica , Cesena, University of Bologna.

SCIENTIFIC EXPERTIES

Techniques for enzymatic dispersion of cells from tissues.
Patch clamp techniques for studying: membrane excitable properties, membrane transporters, ion channels dynamics.
Conventional and confocal micro-fluorescence for studying: intracellular ion dynamics and intercellular ion communication.
Mathematical modelling of cardiac cellular excitability and ion dynamics.

MAIN FIELD OF INTEREST

Modulation of cardiac cellular repolarization: role of electrotonic interaction and of pharmacological modulation.