- Curriculum Vitae
Prof. G Pelosi graduated magna cum laude in 1987 from the University of Parma and from the same institution he received his PhD degree under the supervision of prof. M. Nardelli.
His academic career began in 1991 with his appointment as a researcher at the Faculty of Mathematical, Physical and Natural Sciences of the University of Parma and from his appointment to 1999 he taught "Stoichiometry" to the students of Biological Sciences parallel to the course of “General and Inorganic Chemistry”.
Following his appointment to Associate Professor in 1998 he was assigned, and held until 2002, the course of “Laboratory of Chemistry” for the degree of Biological Sciences. Since 1997 he has been holding the course of “Bioinorganic Chemistry” and since 1999 he has been teaching “General and Inorganic Chemistry” to the students of the degree of Biotechnology, a course that has now become his main teaching responsibility.
In 2004 he was assigned the courses of "Bioinorganic Chemistry" for the second level degree in Chemistry and the course of "Bioinorganic Chemistry and Biocrystallography" for the second level degree in Molecular Biology.
His scientific activity started with systematic studies concerning the coordination chemistry of rigid polydentate ligands with bismuth, subject on which he developed his thesis for his first degree in Chemistry. His work was subsequently extended to the chemistry of inorganic materials with optical and magnetic properties starting from derivatives of bismuth and antimony and extending later to chlorocadmates and iodocuprates. In this area he worked on the chemistry of donor-acceptor systems such as bismuth and antimony-pi-arenes, and more specifically on the structural characterization of charge-transfer compounds between bismuth and antimony halides with paracyclophanes and dibenzosuberanes.
During his doctoral period his interest in crystallography led him into contact with the crystallography of metalloproteins and consequently with the world of bioinorganic chemistry. In this period he managed to gain experience in synchrotron data collection and resolution of crystal structures of proteins. This experience allowed him to spend a year as a postdoc in the Laboratory of Molecular Biophysics at the University of Oxford (United Kingdom) where he worked on the structural characterization of the iron-dependent enzyme isopenicillin-N synthase.
From this moment on, his scientific interest remained in the bioinorganic chemistry area. After getting a permanent position as a researcher, prof. Pelosi has devoted his research to the field of metal thiosemicarbazonates as substances possessing biological activities. The progress of his research in this field is confirmed by the large number of publications in international journals of high impact both in the chemical and the biomedical fields.
More recently he has also begun a collaboration with the group of prof. Policar at the Ecole Normale Supérieure in Paris on the superoxide dismutase activities of complexes of nickel, cobalt, manganese obtained from ligands that have a sugar scaffold and, as arms, heterocyclic systems.
Currently the focus of his research is on the understanding of the mechanisms at the cellular level with which metal thiosemicarbazonates act on tumor cell lines by interfering in some cases on proliferation and often inducing apoptosis.
The work of Prof. Pelosi is highlighted by more than 130 publications in international scientific journals and by the presentation of his achievements at over 50 national and international conferences and meetings.
Completion accademic year: 2019/2020
Completion accademic year: 2018/2019
Completion accademic year: 2017/2018
Completion accademic year: 2016/2017
Completion accademic year: 2015/2016
Completion accademic year: 2014/2015
- Second cycle degree CHEMISTRY A.Y. 2019/2020
- First cycle degree (DM 270) CHEMISTRY A.Y. 2019/2020
- Second cycle degree INDUSTRIAL CHEMISTRY A.Y. 2019/2020
- First cycle degree (DM 270) CHEMISTRY A.Y. 2018/2019
- Second cycle degree CHEMISTRY A.Y. 2018/2019
- Second cycle degree INDUSTRIAL CHEMISTRY A.Y. 2018/2019
- Second cycle degree CHEMISTRY A.Y. 2017/2018
- Second cycle degree INDUSTRIAL CHEMISTRY A.Y. 2017/2018
Sabotage at the powerhouse? Unraveling the Molecular Target of 2-Isopropylbenzaldehyde Thiosemicarbazone, a Specific Inhibitor of Aflatoxin Biosynthesis and Sclerotia Development in Aspergillus flavus, Using Yeast as a Model SystemYear: 2019Author/s: Dallabona C., Pioli M., Spadola G., Orsoni N., Bisceglie F., Lodi T., Pelosi G., Restivo F. M., Degola F.
Cytotoxic activity of copper(ii), nickel(ii) and platinum(ii) thiosemicarbazone derivatives: Interaction with DNA and the H2A histone peptideYear: 2019Author/s: Bisceglie F., Orsoni N., Pioli M., Bonati B., Tarasconi P., Rivetti C., Amidani D., Montalbano S., Buschini A., Pelosi G.
Naphthochromenones: Organic Bimodal Photocatalysts Engaging in Both Oxidative and Reductive Quenching ProcessesYear: 2019Author/s: Javier Mateos, Francesco Rigodanza, Alberto Vega‐Peñaloza, Andrea Sartorel, Mirco Natali, Tommaso Bortolato, Giorgio Pelosi, Xavier Companyó, Marcella Bonchio, Luca Dell'Amico
Year: 2019Author/s: Bisceglie, Franco, Bacci, Cristina, Vismarra, Alice, Barilli, Elena, Pioli, Marianna, Orsoni, Nicolò, Pelosi, Giorgio
Year: 2018Author/s: Bisceglie, Franco, Tavone, Matteo, Mussi, Francesca, AZZONI, SIMONE, Montalbano, Serena, Franzoni, Susanna, Tarasconi, Pieralberto, Buschini, Annamaria, Pelosi, Giorgio