
- Curriculum Vitae
- Teaching
- Appointments
- Research
Personal Data • Date of birth: March 9, 1967 • Place of birth: Parma • Citizenship: Italian • e-mail address: roberta.alfieri@unipr.it • Work address: Department of Medicine and Surgery, Laboratory of Experimental Oncology. University of Parma Via Volturno, 39 43126 Parma Tel. +390521033768; Fax: +390521033742 Education • October, 1996: PhD in Biology and Molecular Pathology • November 15, 1990: Biological Science Degree, University of Parma, Italy (Score 110/110 cum laude) Research Experience • 2006-2018: Associate Professor of General Pathology at University of Parma. Teacher of General Pathology and Immunology. Member of the Board of the Ph.D. School in Medicine of the University of Parma • 1999-2005: Assistant Professor, University of Parma • 1997-1999: post-doctoral fellowship • Head of Unit of Medicine and Experimental Surgery of the Interdepartmental Centre for Innovation in Health Products BIOPHARMANET-TEC. • Principal Investigators of International grants: : 2012-2013 “Does the maintenance of gefitinib exert a benefit in NSCLC cell lines become resistant after a prolonged gefitinib treatment?” AstraZeneca Global 2013-2015: “Integration of gefitinib and conventional chemotherapy in preventing or retarding the acquisition of gefitinib resistance in NSCLC cell lines” AstraZeneca Global 2015-2017: “Effect of combining Osimertinib with conventional chemotherapy or monoclonal antibodies versus HER family in NSCLC cell lines carrying activating mutations” AstraZeneca Global 2018-2020: “Preclinical evaluation of mechanisms of intrinsic resistance to osimertinib” AstraZeneca Global • Co-investigator of Grants from: AIRC IG 2009: “Optimizing EGFR inhibitor treatment in NSCLC” PI: A. Ardizzoni Italian Minister of Health grant 2006-2009“Biological predictive factors of response to target therapies in lung cancer”. PI A. Ardizzoni AIRC IG 2013: “Novel molecularly targeted approaches in the treatment of Squamous Cell Cancer of the Lung” PI A. Ardizzoni AIRC IG 2016:” Study of PD-L1 and other immunotherapy efficacy predictors on cytology and circulating tumor cells in advanced NSCLC”. PI A. Ardizzoni AIRC IG 2017: “Beyond third-generation TKI in EGFR mutated NSCLC: resistance mechanisms, novel combinations and synthesis of new agents” PI M. Tiseo Novartis Farma: 2013-2015“Anti-tumor activity and molecular mechanisms of NVP-BGJ398 in NSCLC: studies in vitro and in xenotransplanted nude mice”; Novartis Farma:2012-2013 “Effect of BKM120 and BYL719 alone or in combination with EGFR TK inhibitors in NSCLC cell lines”; Professional Memberships • Member of the Editorial Advisory Board of Biochemical Pharmacology • Reviewer for: OncoTarget, Oncogene, Molecular Cancer Therapeutics, Molecular Cancer, Mol. Carcinogenesis, PLOS One, Journal of Thoracic Oncology, Journal of Oncopathology, British Journal of Cancer, Pharmacology and Therapeutics, Recent Patent on Anti-Cancer Drug Discovery, J. Cancer Research and Clinical Oncology, Pharmaceutical Design Journal, Medicinal Research Review, J of Experimental and Clinical cancer Research. • Member of: American Society for Investigative Pathology, European Association for Cancer Research, Italian Cancer Society, Italian Pathology Society, Cellular Biology and Differentiation Society. Scientific Production • Co-Author of 88 papers published on peer-reviewed international journals for a total impact factor of around 350 an average impact factor of 4.6, total citation of 1797 and total H-index of 27 (Scopus) • Patents: Alfieri R., Bordi F., Carmi C, Cavazzoni A., Lodola A, Mor M, Petronini PG, Vezzosi S. Composti inibitori irreversibili di EGFR con attività antiproliferativa PCT/IB2009/055980 Bernini F., Adorni M.P., Petronini P.G., Alfieri R, Galetti M., Favari E., Incerti M. New MDR1 inhibitors to overcome multidrug resistance PCT/EP2015/067795 Research activity The scientific interest is focused on Translational Research in Non Small Cell Lung Cancer. In particular she has been involved in the exploration in pre-clinical models, both in-vitro and in xenotransplanted nude mice, of the efficacy of new therapeutic strategies to prevent/overcome targeted drug resistance.
Anno accademico di erogazione: 2020/2021
- Course year: 1 - First cycle degree (DM 270) - MIDWIFERY - A.Y.: 2020/2021
- Course year: 2 - Full cicle (6 years) - MEDICINE AND SURGERY - A.Y.: 2019/2020
- Course year: 3 - Full cicle (5 years) - PHARMACEUTICAL CHEMISTRY AND TECHNOLOGY - A.Y.: 2018/2019
- Course year: 2 - First cycle degree (DM 270) - BIOMEDICAL LABORATORY TECHNIQUES - A.Y.: 2019/2020
- Course year: 5 - Full cicle (5 years) - PHARMACY - A.Y.: 2016/2017
Anno accademico di erogazione: 2019/2020
- Course year: 1 - First cycle degree (DM 270) - MIDWIFERY - A.Y.: 2019/2020
- Course year: 2 - Full cicle (6 years) - MEDICINE AND SURGERY - A.Y.: 2018/2019
- Course year: 3 - Full cicle (5 years) - Pharmaceutical chemistry and technology - A.Y.: 2017/2018
- Course year: 2 - First cycle degree (DM 270) - BIOMEDICAL LABORATORY TECHNIQUES - A.Y.: 2018/2019
- Course year: 5 - Full cicle (5 years) - PHARMACY - A.Y.: 2015/2016
Anno accademico di erogazione: 2018/2019
- Course year: 1 - First cycle degree (DM 270) - MIDWIFERY - A.Y.: 2018/2019
- Course year: 2 - Full cicle (6 years) - MEDICINE AND SURGERY - A.Y.: 2017/2018
- Course year: 3 - Full cicle (5 years) - Pharmaceutical chemistry and technology - A.Y.: 2016/2017
- Course year: 2 - First cycle degree (DM 270) - BIOMEDICAL LABORATORY TECHNIQUES - A.Y.: 2017/2018
- Course year: 5 - Full cicle (5 years) - PHARMACY - A.Y.: 2014/2015
Anno accademico di erogazione: 2017/2018
- Course year: 1 - First cycle degree (DM 270) - MIDWIFERY - A.Y.: 2017/2018
- Course year: 1 - First cycle degree (DM 270) - AUDIOPROTHESIC TECHNIQUES - A.Y.: 2017/2018
- Course year: 2 - Full cicle (6 years) - Medicine and Surgery - A.Y.: 2016/2017
- Course year: 3 - Full cicle (5 years) - Pharmaceutical chemistry and technology - A.Y.: 2015/2016
- Course year: 2 - First cycle degree (DM 270) - Biomedical Laboratory techniques - A.Y.: 2016/2017
- Course year: 2 - First cycle degree (DM 270) - Biomedical Laboratory techniques - A.Y.: 2016/2017
- Course year: 5 - Full cicle (5 years) - PHARMACY - A.Y.: 2013/2014
Anno accademico di erogazione: 2016/2017
- Course year: 1 - First cycle degree (DM 270) - Midwifery - A.Y.: 2016/2017
- Course year: 1 - First cycle degree (DM 270) - AUDIOPROTHESIC TECHNIQUES - A.Y.: 2016/2017
- Course year: 2 - Full cicle (6 years) - Medicine and Surgery - A.Y.: 2015/2016
- Course year: 3 - Full cicle (5 years) - Pharmaceutical chemistry and technology - A.Y.: 2014/2015
- Course year: 2 - First cycle degree (DM 270) - Biomedical Laboratory techniques - A.Y.: 2015/2016
- Course year: 2 - First cycle degree (DM 270) - Biomedical Laboratory techniques - A.Y.: 2015/2016
Anno accademico di erogazione: 2015/2016
- Course year: 1 - First cycle degree (DM 270) - Midwifery - A.Y.: 2015/2016
- Course year: 1 - First cycle degree (DM 270) - AUDIOPROTHESIC TECHNIQUES - A.Y.: 2015/2016
- Course year: 2 - Full cicle (6 years) - Medicine and Surgery - A.Y.: 2014/2015
- Course year: 3 - Full cicle (5 years) - Pharmaceutical chemistry and technology - A.Y.: 2013/2014
- Course year: 2 - First cycle degree (DM 270) - Biomedical Laboratory techniques - A.Y.: 2014/2015
- Course year: 2 - First cycle degree (DM 270) - Biomedical Laboratory techniques - A.Y.: 2014/2015
Anno accademico di erogazione: 2014/2015
- Course year: 1 - First cycle degree (DM 270) - AUDIOPROTHESIC TECHNIQUES - A.Y.: 2014/2015
- Course year: 1 - First cycle degree (DM 270) - Midwifery - A.Y.: 2014/2015
- Course year: 2 - Full cicle (6 years) - Medicine and Surgery - A.Y.: 2013/2014
- Course year: 2 - First cycle degree (DM 270) - Biomedical Laboratory techniques - A.Y.: 2013/2014
- Course year: 2 - First cycle degree (DM 270) - Biomedical Laboratory techniques - A.Y.: 2013/2014
- Course year: 2 - Full cicle (5 years) - Pharmaceutical chemistry and technology - A.Y.: 2013/2014
Anno accademico di erogazione: 2013/2014
- Course year: 1 - First cycle degree (DM 270) - Midwifery - A.Y.: 2013/2014
- Course year: 1 - First cycle degree (DM 270) - AUDIOPROTHESIC TECHNIQUES - A.Y.: 2013/2014
Teacher tutor
- First cycle degree (DM 270) BIOMEDICAL LABORATORY TECHNIQUES A.Y. 2020/2021
- First cycle degree (DM 270) BIOMEDICAL LABORATORY TECHNIQUES A.Y. 2019/2020
- First cycle degree (DM 270) BIOMEDICAL LABORATORY TECHNIQUES A.Y. 2018/2019
- First cycle degree (DM 270) BIOMEDICAL LABORATORY TECHNIQUES A.Y. 2017/2018
- First cycle degree (DM 270) Biomedical Laboratory techniques A.Y. 2016/2017
- First cycle degree (DM 270) Biomedical Laboratory techniques A.Y. 2015/2016
- First cycle degree (DM 270) Biomedical Laboratory techniques A.Y. 2014/2015
- First cycle degree (DM 270) Biomedical Laboratory techniques A.Y. 2013/2014
Professor/Teacher
- First cycle degree (DM 270) MIDWIFERY A.Y. 2020/2021
- First cycle degree (DM 270) MIDWIFERY A.Y. 2019/2020
- First cycle degree (DM 270) MIDWIFERY A.Y. 2018/2019
- First cycle degree (DM 270) MIDWIFERY A.Y. 2017/2018
- Full cicle (6 years) Medicine and Surgery A.Y. 2016/2017
- Full cicle (6 years) Medicine and Surgery A.Y. 2015/2016
- Full cicle (6 years) Medicine and Surgery A.Y. 2014/2015
Publications
-
Year: 2021Author/s: Monica S. L., Fumarola C., Cretella D., Bonelli M., Minari R., Cavazzoni A., Digiacomo G., Galetti M., Volta F., Mancini M., Petronini P. G., Tiseo M., Alfieri R.
-
Year: 2020Author/s: Rebuzzi, Sara Elena, Alfieri, Roberta, La Monica, Silvia, Minari, Roberta, Petronini, Pier Giorgio, Tiseo, Marcello
-
Year: 2020Author/s: Digiacomo G., Fumarola C., La Monica S., Bonelli M. A., Cretella D., Alfieri R., Cavazzoni A., Galetti M., Bertolini P., Missale G., Petronini P. G.
-
Year: 2020Author/s: Cavazzoni A., Digiacomo G., Alfieri R., La Monica S., Fumarola C., Galetti M., Bonelli M., Cretella D., Barili V., Zecca A., Giovannetti E., Fiorentino M., Tiseo M., Petronini P. G., Ardizzoni A.
-
Year: 2020Author/s: Bonelli M., Terenziani R., Zoppi S., Fumarola C., La Monica S., Cretella D., Alfieri R., Cavazzoni A., Digiacomo G., Galetti M., Petronini P. G.