Personale docente

PRESENT POSITIONS
Full Professor of Hematology at the University of Parma, Italy
Physician Executive at the “U.O. di Ematologia-Azienda Ospedaliero-Universitaria” of Parma

Titles and Positions
• (07/09/1993) Graduated in Medicine and Surgery at the University of Florence (Italy) with the score of 110/110 and “first class honors degree”.
• (11/29/1999) Specialized in Internal Medicine at the University of Parma (Italy) with the score of 50/50 and “first class honors degree”.
• (March 1999-September 2000) Fellowship in Hematology at the INSERM U463, Nantes (France) on the pathopshysiology of bone lesions in multiple myeloma and the role of RANKL in myeloma-induced osteoclast formation. (Prof. Regis Bataille)
• (Jannuary 2001-2003) PhD degree at the University of Parma with a thesis entitled: “Role of RANKL in the pathophysiology of bone lesions in multiple myeloma”
• (February 2001-November 2010): Assistant Professor in Hematology belonging at the “Cattedra di Ematologia” of the University of Parma.
• (July 2004 and July 2008) Visiting at the Department of Medicine, Division of Hematology- Oncology”, University of Pittsburgh (USA) (Prof. G.D. Roodman) for a collaborative studies on the role of IL-3 in the pathosphysiology of bone lesions in multiple myeloma.
• (November 2010-until now). Associate Professor of Hematology at the University of Parma.
• (November 2010-until now). Head of the Research Laboratory of Hematology at the University of Parma.
•Full professor in Hematology since March 2021

Participation in committees
• Member of the board of the Ph.D. in “Medical Science” of the University of Parma from 2011.
• Member of the Local Research Board of the “Azienda Ospedaliero-Universitaria di Parma” from April 2011.
• Member of “Jury de thèse” at the University of Nantes (France), October 2009
• Member of the Medical Research Committee of the University of Parma from 2011

Awards and Grants
International
• Grant of the “Ligue Nationale Contre le Cancer", Nantes, (France), 1999-2000.
• “Young Investigator Award” of the American Society for Bone and Mineral Research (ASBMR) in the 2001 for the work entitled: “Human myeloma cells upregulate RANKL and downregulate OPG in Bone Environment: Evidence of OPG/RANKL Imbalance in Multiple Mieloma patients”
• “Travel Grant” at the annual meeting of International Society of Experimental Hematology (ISEH) in 2003 and 2004.
• “Travel Grant” al “Vth International Conference on cancer-induced bone disease”, Davos (Svizzera), 2005.
• Junior Award Grant of the ”International Myeloma Foundation” in 2006 for the work entitled: “Role of Wnt and Runx2 pathways in the inhibitions of osteoblasts in multiple myeloma patients”
• Senior Award Grant of the”International Myeloma Foundation” in the 2009 for the work entitled: “Study of alterations of bone microenvironment cells in multiple myeloma patients in relationship with osteolytic bone lesions: identification of potential new therapeutic targets”.
• Senior Grant of the “International Myeloma Foundation Brian D. Novis” in the 2018 for the research: “Reprogramming MM cell metabolism to affect bone disease in Multiple Myeloma.

National
• Group Leader of Grants of the Italian Minister of University and Research (MIUR) in the 2004 entitled: “Espressione e ruolo delle isoforme del recettore chemochinico CXCR3 nella fisiopatologia del mieloma multiplo e delle neoplasie B” and 2006 entitled “Alterazioni del microambiente osseo nel mieloma multiplo: meccanismi biologici e ruolo patogenetico”
• Principal Investigator of the Grant of the “Associazione Italiana Ricerca sul Cancro” (AIRC), Grant application IG2009 for a project entitled “Bone cell alterations in multiple myeloma patients and effects of new drugs”.
• Group Leader of the Grant AIRC 5/1000 Special Program Molecular Clinical Oncology, in 2010, with a project entitled “Harnessing tumour cell/microenvironment cross talk to treat mature B-cell tumours”. (Cord. Prof. Caligaris Cappio).
• Principal Investigator of the Grant of the “Associazione Italiana Ricerca sul Cancro” (AIRC), Grant application IG2014 for a project entitled “HYPOXIC NICHE AS A POTENTIAL THERAPEUTIC TARGET IN MYELOMA BONE MICROENVIRONMENT”.
• Principal Investigator of the IG2017-2022 of the “Associazione Italiana Ricerca sul Cancro” (AIRC) for a project entitled "Glutamine metabolism for targeting and imaging in myeloma bone microenvironment".
• Principal Investigator of the “Ministero della salute Ricerca Finalizzata 2016”, for the Italian researcher abroad project entitled "IDENTIFICATION AND VALIDATION OF CRITICAL 1q21 ACHILLE’S HEEL VULNERABILITIES IN MULTIPLE MYELOMA PATIENTS.”.

Oral presentations at International Congress with referee
• “American Society of hematology” (ASH): oral communication at the annual meeting in the 2001, 2004, 2006 (2 communications), 2009 (4 communications), 2010 (2 communications), 2014 and 2016.
• “European Society of hematology” (EHA): oral communication at the annual meeting in the 2002, 2003 and 2007.
• International Society for Experimental hematology” (ISEH): oral communication at the annual meeting in the 2003, 2004, 2005, 2006, 2007 and 2008.

Invited lectures at foreign Universities, Institutions and International Congress
• “Multiple Myeloma bone disease: from the pathophysiology to the treatment” (Invited by O. Sezer), Berlin, May 2007
• “Pathophysiology of Multiple Myeloma bone disease”, Harvard Medical School, Masachussetts General Hospital, Boston, MA (Invited by Dr. Noopur Raje) July 2008
• “Pathophysiology of Multiple Myeloma bone disease and the effects of the new drugs on the bone microenvironment” Centre Pluridisciplinaire d'Oncologie, CFH, Lausanne, Suisse (Invited by Dr. Nicholas Ketterer, April 2009.
• “Pathophysiology of osteoclast activation in Multiple Myeloma”. Institute for Research in Biomedicine, Bellinzona, Suisse (Invited by Antonio Lanzavecchia), November 2009.
• "Eleventh International ABMT Symposium", Arlington, (USA), 2002
• “Eurocancer 2008”, Parigi (Francia), 2008
• “Eticho Multiple Myeloma 2010 course”, Madrid, May, 2010
• “13th International Myeloma Workshop”, Paris, May 2011

Peer reviewer: Peer reviewer activity for the following Journals: Blood, Leukemia, Haematologica, Leukemia Research, Journal of Clinical Investigation.

Memberships: He is member of the International Society of Experimental Hematology (ISEH) and of the American Society of Hematology (ASH), Italian Society of Experimental Hematology (SIES) and Italian Society of Hematology (SIE).

Teachings
• (February 2001-until now) Professor of Hematology at the Faculty of Medicine and Surgery of the University of Parma.
• (November 2007-until now) Professor at the Faculty of Biotechnology of the University of Parma with a Course on “Hematopoietic stem cell biology and clinical application”.
• (November 2002-until now) Professor of Hematology and at the Hematology, Oncology, Internal Medicine, Dermatology, Endocrinology and Gynecology School of Specialization at the Faculty of Medicine and Surgery of the University of Parma.
• (January 2011-until now) Head of the MASTER in “Stem cell and Regenerative Medicine of the University of Parma

 
Publications in international scientific journals with referee
Number: 149
• Impact factor (IF) 925 (average IF : 6.2)
• First/last author IF (n° 78): 461 (average IF: 5.9)
• WOS: H-index 40; Scopus: H-index 41;