- Curriculum Vitae
Franco Bisceglie was born in Cremona (Italy) on august 14, 1972. He graduated from the University of Parma in 1997 with a thesis entitled “Synthesis of SNO coordinating systems owning a biological activity”. From the same institution he received his PhD degree with a doctoral thesis entitled “Preparative, spectral and structural studies of new metal complexes with polydentate ligands of medical applicative interest”. He also worked worked on a research project for the “Synthesis of Tripodal Ligands C-centred. Preparation, Characterization, Reaction with Superoxide of the Corresponding Fe(II) and Mn(II) Complexes and Biological Activity” at the Laboratoire de Chimie Bioorganique et Bioinorganique (LCBB) of the Institut de Chimie Moléculaire et des Matérieux d’Orsay (ICMMO) at Paris XI University in the group of prof. I. Morgenstern-Badarau and under the supervision of prof. F. Lambert. He was recipient of two fellowships advertised by the “Inter-university consortium for the study of metals in biological systems (C.I.R.C.M.S.B.) to perform research projects in the field of “Metal ions in human diagnostic and therapy” and “ New inorganic drugs in oncology”. He was also appointed for several projects for the research, synthesis and characterization of non-cisplatin like metal complexes as anti-tumor agents.
In 2004 he obtained cum laude a Master of Science in “Quality Control and Chemical Analysis Methods Validation” with a thesis entitled “Validation of an analytical method and experimental design for products in stability studies: two critical aspects in the drug research, improvement and revisions for processes optimization”.
In 2005 Franco Bisceglie was appointed researcher at the University of Parma.
Presently his work centres on the chemistry and biological properties of thiosemicarbazone metal complexes, in particular with copper and metals of the first transition series. Recently his interest is focused on the synthesis of thiosemicarbazones bearing a glycosidic moiety that could increase the water solubility and/or bioavailability of the systems under study. Moreover his attention has focused on the inclusion of metal complexes in liposomes in order to build systems that could better drive the metal complexes under study in the culture media.
He is author of about 50 papers and several presentations to conferences.
Completion accademic year: 2019/2020
Completion accademic year: 2018/2019
Completion accademic year: 2017/2018
Completion accademic year: 2016/2017
Completion accademic year: 2015/2016
Sabotage at the powerhouse? Unraveling the Molecular Target of 2-Isopropylbenzaldehyde Thiosemicarbazone, a Specific Inhibitor of Aflatoxin Biosynthesis and Sclerotia Development in Aspergillus flavus, Using Yeast as a Model SystemYear: 2019Author/s: Dallabona C., Pioli M., Spadola G., Orsoni N., Bisceglie F., Lodi T., Pelosi G., Restivo F. M., Degola F.
Cytotoxic activity of copper(ii), nickel(ii) and platinum(ii) thiosemicarbazone derivatives: Interaction with DNA and the H2A histone peptideYear: 2019Author/s: Bisceglie F., Orsoni N., Pioli M., Bonati B., Tarasconi P., Rivetti C., Amidani D., Montalbano S., Buschini A., Pelosi G.
A contribute to the comprehension of complexing agents and salt solutions reaction mechanism on chemical attack of type I molded glass containersYear: 2019Author/s: Biavati, Alberto, Severi, Giorgia, Marchegiani, Milena, Ferrarini, Arianna, Bisceglie, Franco
Year: 2019Author/s: Bisceglie, Franco, Bacci, Cristina, Vismarra, Alice, Barilli, Elena, Pioli, Marianna, Orsoni, Nicolò, Pelosi, Giorgio
Year: 2018Author/s: Bisceglie, Franco, Tavone, Matteo, Mussi, Francesca, AZZONI, SIMONE, Montalbano, Serena, Franzoni, Susanna, Tarasconi, Pieralberto, Buschini, Annamaria, Pelosi, Giorgio