Lorenzo Tagliazucchi

Fixed-term researcher

Department of Food and Drug

SSD: Pharmaceutical Chemistry (CHEM-07/A)

Contacts

E. lorenzo.tagliazucchi@unipr.it

Office: Campus Scienze e Tecnologie - Padiglione 08 - Plesso di Farmacia

Address: Parco Area delle Scienze 27/A, 43124 Parma

Teachings

Academic year of provision: 2026/2027

Laboratory of Instrumental Pharmaceutical Analysis

Single-cycle degree course 5 years in PHARMACEUTICAL CHEMISTRY AND TECHNOLOGY

Year: 3°

Research

Publications

The rare bile acid isoallolithocholic acid (IALCA) is an EphA2 antagonist sparing FXR and TGR5 receptors

Authors: Blesio Andrea; Giorgio Carmine; Ferrari Francesca Romana; Sala Stefano; Flammini Lisa; Zanotti Ilaria; Passeri Daniela; Gioiello Antimo; Sarcone Lorenzo; Castelli Riccardo; Karnchanapandh Kun; Vacondio Federica; Tagliazucchi Lorenzo; Scalvini Laura; Mor Marco; Lodola Alessio; Tognolini Massimiliano

Year: 2026
Mass Spectrometry Proteomics: A Key to Faster Drug Discovery

Authors: Tagliazucchi Lorenzo; Costi Maria Paola

Year: 2026
Identification of isoxazole-based TRPA1 inhibitors with analgesic effects in vivo

Authors: Albanese Valentina; Marini Matilde; Tesi Martina; Landini Lorenzo; Bellantoni Elisa; Cosconati Sandro; Roggia Michele; Tagliazucchi Lorenzo; Gnudi Lorenzo; Puscio Valentina; Sturaro Chiara; Ruzza Chiara; Guerrini Remo; Geppetti Pierangelo; Nassini Romina; Preti Delia; De Logu Francesco; Pacifico Salvatore

Year: 2025
Identification of pyrazolo-piperidinone derivatives targeting YAP-TEAD interface 3 as anticancer agents through integrated virtual screening and mass spectrometry proteomics

Authors: Scalvini L.; Tagliazucchi L.; Elisi G. M.; Zappaterra D.; Moschella M. G.; Fantini S.; Aiello D.; Guerrini R.; Albanese V.; Pacifico S.; Lopresti L.; Malpezzi G.; Saporito G.; Ferrari S.; Lamesta M.; Losi L.; Pozzi C.; Mangani S.; Marverti G.; Venturelli A.; Ponterini G.; D'Arca D.; Mor M.; Costi M. P.

Year: 2025
Leveraging proteomics, bioinformatics, and ecotoxicology models to select new targets overcoming L infantum drug resistance

Authors: Tagliazucchi Lorenzo; Malpezzi Giulia; Brooks Bryan W.; Thoré Eli S. J.; Bertram Michael G.; Gamarro Francisco; Paola Costi Maria

Year: 2024

Full list of publications

Public Engagement Initiatives

Deposito domanda internazionale secondo PCT (WO 2025/126129 A1 del 19/6/2025)

Deposito della domanda di brevetto dal titolo "Nuovi prodotti anti-TEAD attivi verso i tumori sensibili e resistenti N. 102023000026622 / Compounds with antitumor activity directed at the Hippo pahtway WO 2025/126129 A1. Invenzione relativa a nuovi composti agenti sul sistema YAP-TEAD per il trattamento di sottotipi tumorali solidi, incluso tumore all’ovario, polmone, alla mammella, al colon retto, pancreatico, epatico, melanoma cutaneo e glioma.

Date: 19/06/2025

Contacts

Teacher's social media

Teacher's activities

Teachings

Laboratory of Instrumental Pharmaceutical Analysis

Research

Publications

The rare bile acid isoallolithocholic acid (IALCA) is an EphA2 antagonist sparing FXR and TGR5 receptors

Mass Spectrometry Proteomics: A Key to Faster Drug Discovery

Identification of isoxazole-based TRPA1 inhibitors with analgesic effects in vivo

Identification of pyrazolo-piperidinone derivatives targeting YAP-TEAD interface 3 as anticancer agents through integrated virtual screening and mass spectrometry proteomics

Leveraging proteomics, bioinformatics, and ecotoxicology models to select new targets overcoming L infantum drug resistance

Public Engagement Initiatives

Deposito domanda internazionale secondo PCT (WO 2025/126129 A1 del 19/6/2025)