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Alma universitas studiorum parmensis A.D. 962 - Università di ParmaAlma universitas studiorum parmensis A.D. 962 - Università di Parma People and Organization
Università degli Studi di Parma

Silvia Rivara

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Full professor
Department of Food and Drug
SSD: Pharmaceutical Chemistry (CHEM-07/A)

Curriculum Vitae

1995: degree in Medicinal Chemistry and Pharmaceutical Technology, University of Parma (Italy).
1999: Ph.D. degree in Medicinal Chemistry and Pharmaceutical Technology, University of Pavia (Italy).
1998-2005: assistant professor of Medicinal Chemistry, University of Parma.
 2005-2018: associate professor of Medicinal Chemistry, Department of Food and Drug, University of Parma.
2018-: full professor of Medicinal Chemistry, Department of Food and Drug, University of Parma.
2013-2018: member of the Scientific Committee for Chemical Sciences Area, University of Parma.
2014-2015: Director of the Library of the Faculty of Pharmacy.
2017-: Delegate of the Director of the Department of Food and Drug for teaching activities.
2018 -: visiting professor of the University of Lincoln (UK), School of Pharmacy.
Member of the Teachers Board of the Ph.D in Drugs, Biomolecules and Health Products, University of Parma.
Editorial board member for Journal of Pineal Research, Current Pharmaceutical Design, PeerJ.
Teaching activity of medicinal chemistry courses for the Degree in Pharmacy and for the School of Hospital Pharmacy, University of Parma.
Teaching activity for the Master in Drug Design and Development, University of Pavia.

Positions

University of Lincoln (UK), School of Pharmacy, 2018-2021.

Teaching

Research

Research areas

Research interests: drug design, structure-activity relationships and ligand-target interaction studies in different fields of pharmaceutical interest. Application of chemoinformatics to medicinal chemistry projects allows investigation on the mechanisms of action and on the structural requirements important for biological activity of drugs. Information acquired from these studies is applied to the design of novel compounds acting on biological targets involved in new therapeutic strategies. The main research fields are related to the design and structure-activity relationships evaluation for new compounds acting as: - ligands of the melatonin membrane receptors MT1 and MT2; - compounds acting on the endocannabinoid system; - inhibitors of tyrosine kinase receptors (EGFR, FGFR); - inhibitors of the enzyme heparanase; - RNA polymerase inhibitors as antibacterial agents.

Publications

Full list of publications

Public Engagement Initiatives

Gobbi G., Mor M., Rivara S., Fraschini F., Tarzia G., Bedini A., Spadoni G., Lucini V. Novel melatonin ligands having antidepressant activity as well as sleep inducing properties.  US patent: US 8,791,163 granted on July 29, 2014; European patent:  EP1973868(B1) granted on September 9, 2015.

  • XXIX National Meeting in Medicinal Chemistry

    NMMC è il congresso di bandiera della Divisione di Chimica Farmaceutica e rappresenta la migliore opportunità per condividere i progressi nella ricerca e favorire collaborazioni tra ricercatori provenienti sia dal mondo accademico che dall'industria. Gli oltre 350 partecipanti iscritti alla XXIX edizione hanno avuto la possibilità di seguire interventi scientifici tenuti da esperti di livello internazionale che copriranno i più recenti progressi nel campo della chimica farmaceutica, come la modulazione dei segnali lipidici come strategia per realizzare nuovi approcci terapeutici, l’uso dell’intelligenza artificiale e dei metodi computazionali nella progettazione di farmaci, l’utilizzo di tecniche biofisiche per la caratterizzazione dell’interazione tra farmaci e bersagli molecolari e la sostenibilità ambientale.

    Date: 14/09/2025-17/09/2025