Personale docente

PERSONAL INFORMATION Date of birth: 27 March 1964 Place of birth: Parma, Italy Citizenship: Italian Language fluency: English Status: Married, four children Current Position: Assistant Professor of Pathology - Dept. SBiBiT (Scienze Biomediche, Biotecnologiche e Traslazionali), University of Parma, via Volturno 39, 43125 Parma, Italy EDUCATION AND WORK EXPERIENCE 1988, Master’s degree in Biological Sciences, University of Parma, Italy 1994, Ph.D in Molecular Biology and Pathology, University of Parma From 1990 to 2001: Research Assistant, Institute of General Pathology, University of Parma Since 2001: Assistant Professor of Pathology (tenured), Dept. SBiBiT (Scienze Biomediche, Biotecnologiche e Traslazionali), University of Parma TEACHING Educational courses entrusted to Dr. Rotoli: - M.A. Degree in Biology and Biomedical Applications: Commitment of 6 credits in the course of Molecular Pathology (from 2013) - M.D. Degree in Medicine and Surgery: Commitment of 1 credit in the course of General Pathology (from 2010) - B.Sc. Degree in Orthoptists: General Pathology Course (from 2005) - B. Sc. Degree in Nursing: General Pathology Course (2005-2009) - B. Sc. Degree in Speech Therapy: General Pathology Course (from 2004) - B. Sc. Degree in Audiometry and Hearing aids: Physiopathology Course (from 2004) - B.Sc. Degree in Biomedical Laboratory Technicians: Pathology and General Physiopathology Course (2004-2012) - M.A. Degree in Medical, Veterinary and Pharmaceutical Biotechnology Biotecnology Techniques of in vitro cell cultures in the Course "Regeneration of differentiated tissues" (2012-2013) Since 2002 she has been a member of the Board of the Ph. D. Track in Molecular Biology and Pathology, University of Parma. SCIENTIFIC EXPERIENCE She has published, as a co-author, more than 40 scientific publications on international peer reviewed journals (17 as a first Author) plus 1 book Chapter (Barilli A, Rotoli BM et al., Arginine transport in human monocytes/macrophages. In: “Handbook of Macrophages: Life Cycle, Functions and disease”. Nova science Publisher). h-index and citation report: From Google Scholar: Sum of the times cited: 815 From 2010: 405 h-index: 17 From 2010: 13 From Web of Science collection: Sum of the times cited: 608 h-index: 15 MAJOR RESEARCH INTERESTS: 1) functional activity of transporters for amino acids and other solutes in mammalian cells and their role in human pathological conditions. 2) role of arginine and its metabolites in the macrophage functions and in the modulation of intestinal epithelial permeability in vitro. 3) cytotoxicity of nanomaterials in macrophages and epithelial cells. She has been Principal Investigator or member of Research Staff in several projects funded by public or private Agencies. GRANTS 2004-2006 Principal Investigator, Project “NATURAL AND SYNTHETIC AMINO ACIDS AS CHEMICAL CHAPERONES TO PROMOTE CFTR FOLDING” funded by Fondazione per la Ricerca sulla Fibrosi Cistica - onlus. 2005-2007. Research Unit Responsible, (National Coordinator for 2006-2007) National Project “PATOGENESI DELLA PROTEINOSI ALVEOLARE POLMONARE NELLA LPI: UTILIZZO DI MODELLI CELLULARI IN VITRO PER LO STUDIO DELLA PATOLOGIA”, (MIUR, PRIN "Lysinuric protein intolerance: generation and analysis of a conditional mouse model and of human cellular models." Funds from University of Parma: 2005 - "Employment of amino acids, natural or synthetic, as "chemical chaperones" for the phenotypic correction of CFTR protein" 2006-2008 - "Study of the pathogenetic mechanisms of the Pulmonary Alveolar Proteinosis (PAP) associated to Lysinuric Protein Intolerance (LPI). 2009-2010 Researcher, Research Grant from CLIMB (Children Living with Metabolic Inherited Disease): “TITLE: Study of the pathogenesis of the pulmonary complications in Lysinuric Protein Intolerance (LPI), P.I. Prof. Valeria Dall’Asta 2011-2012 Researcher, Research Grant from CLIMB (Children Living with Metabolic Inherited Disease): “TITLE: Role of arginine and its metabolites in the functions of macrophages isolated from patients affected by Lysinuric Protein Intolerance (LPI), P.I. Prof. Valeria dall’Asta” 2011-2015 Researcher, FP7-263215 - Project “Managing Risks of Nanoparticles” – MARINA (Local Unit Responsible: Prof. Enrico Bergamaschi, Coordinator: Prof. Lang Tran) 2012-2014 Researcher, FP7-280716 - Project “Safe Nano Worker Exposure Scenarios” – SANOWORK. (Local Unit Responsible: Prof. Enrico Bergamaschi, Coordinator: Dott. Anna Luisa Costa)