Personale docente

PERSONAL INFORMATION Date of birth: 27 March 1964 Place of birth: Parma, Italy Citizenship: Italian Language fluency: English Status: Married, four children. Current Position: Associate Professor of Pathology - Dept. Medicine and Surgery, University of Parma, via Volturno 39, 43125 Parma, Italy EDUCATION AND WORK EXPERIENCE 1988, Master’s degree in Biological Sciences, University of Parma, Italy 1994, Ph.D in Molecular Biology and Pathology, University of Parma From 1990 to 2001: Research Assistant, Institute of General Pathology, University of Parma. Since 2001: Assistant Professor of Pathology, University of Parma. TEACHING. General pathology in the degree courses of Medicine and Surgery, Dentistry and Dental Prosthetics, Translational Biomedical Sciences and Professional Educator. SCIENTIFIC EXPERIENCE She has published, as a co-author, more than 60 scientific publications on international peer reviewed journals plus 1 book Chapter (Barilli A, Rotoli BM et al., Arginine transport in human monocytes/macrophages. In: “Handbook of Macrophages: Life Cycle, Functions and disease”. Nova science Publisher). MAJOR RESEARCH INTERESTS: 1) Study of the effects of the SARS-CoV-2 Spike protein on innate immune cells, respiratory epithelial cells, and endothelial cells. 2) Characterization and regulation of amino acid transport across the plasma membrane of normal and diseased human cells. 3) Characterization of transporters involved in drug delivery (ABC transporters, OCT, OCTN) in respiratory epithelial cells (in collaboration with Chiesi Farmaceutici). She has been Principal Investigator or member of Research Staff in several projects funded by public or private Agencies. GRANTS 2004-2006 Principal Investigator, Project “NATURAL AND SYNTHETIC AMINO ACIDS AS CHEMICAL CHAPERONES TO PROMOTE CFTR FOLDING” funded by Fondazione per la Ricerca sulla Fibrosi Cistica - onlus. 2005-2007. Research Unit Responsible, (National Coordinator for 2006-2007) National Project “PATOGENESI DELLA PROTEINOSI ALVEOLARE POLMONARE NELLA LPI: UTILIZZO DI MODELLI CELLULARI IN VITRO PER LO STUDIO DELLA PATOLOGIA”, (MIUR, PRIN "Lysinuric protein intolerance: generation and analysis of a conditional mouse model and of human cellular models." Funds from University of Parma: 2005 - "Employment of amino acids, natural or synthetic, as "chemical chaperones" for the phenotypic correction of CFTR protein" 2006-2008 - "Study of the pathogenetic mechanisms of the Pulmonary Alveolar Proteinosis (PAP) associated to Lysinuric Protein Intolerance (LPI). 2009-2010 Researcher, Research Grant from CLIMB (Children Living with Metabolic Inherited Disease): “TITLE: Study of the pathogenesis of the pulmonary complications in Lysinuric Protein Intolerance (LPI), P.I. Prof. Valeria Dall’Asta 2011-2012 Researcher, Research Grant from CLIMB (Children Living with Metabolic Inherited Disease): “TITLE: Role of arginine and its metabolites in the functions of macrophages isolated from patients affected by Lysinuric Protein Intolerance (LPI), P.I. Prof. Valeria dall’Asta” 2011-2015 Researcher, FP7-263215 - Project “Managing Risks of Nanoparticles” – MARINA (Local Unit Responsible: Prof. Enrico Bergamaschi, Coordinator: Prof. Lang Tran) 2012-2014 Researcher, FP7-280716 - Project “Safe Nano Worker Exposure Scenarios” – SANOWORK. (Local Unit Responsible: Prof. Enrico Bergamaschi, Coordinator: Dott. Anna Luisa Costa)