Fixed-term researcher
Organizational affiliation: Department of Medicine and Surgery
Translational biomedical sciences Unit
SSD: Oral Diseases and Dentistry (MEDS-16/A)

Presentazione

Dr. Benedetta Ghezzi is a fixed-term researcher at the University of Parma in the field of Oral and Dental Diseases. Her research activity focuses on the regeneration of oral tissues through the development and testing of innovative biomaterials and tissue engineering strategies, with particular attention to implant and periodontal applications.

She is involved in teaching activities in the degree programs in Dentistry and Dental Prosthetics, Dental Hygiene, and Medical, Veterinary and Pharmaceutical Biotechnologies. In addition, she is the head of the Biomaterials and Tissue Engineering Laboratory at the University Dental Center.

Curriculum Vitae

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Dr. Benedetta Ghezzi is a Type A researcher in the field of Oral and Dental Diseases (MEDS-16/A) at the Department of Medicine and Surgery of the University of Parma, where she carries out research and teaching activities at the University Dental Center. She is the head of the Biomaterials and Tissue Engineering Laboratory, coordinating its experimental and organizational activities and contributing to the training of students, undergraduates, and early-career researchers.

She obtained her Master’s Degree in Medical, Veterinary and Pharmaceutical Biotechnologies and her PhD in Molecular Medicine – Oral and Dental Diseases at the University of Parma. She is licensed to practice as a Biologist (Section A) and has obtained the National Scientific Qualification for the position of Associate Professor in the MEDS-16/A sector. She has gained research experience both nationally and internationally, including periods as an Honorary Research Fellow at Queen Mary University of London and at the University of São Paulo in Ribeirão Preto, Brazil.

Her research activity focuses on the development and characterization of innovative biomaterials and three-dimensional scaffolds for the regeneration of oral tissues, with particular attention to applications in implantology and periodontology. Her work follows a translational approach, integrating in vitro studies, preclinical models, and clinical trials, with the aim of developing advanced therapeutic solutions for the treatment of oral and dental diseases. She is a principal investigator and co-investigator in numerous competitively funded national and international research projects and is the author of scientific publications in peer-reviewed journals.

She is involved in teaching activities in the degree programs in Dentistry and Dental Prosthetics, Medical, Veterinary and Pharmaceutical Biotechnologies, and Dental Hygiene, and is actively engaged in supervising undergraduate theses and tutoring activities. She also serves on academic and scientific committees within the university and is a member of national and international scientific societies.

Teachings

Research

Research areas

Research activity focuses on the development and application of innovative biomaterials for the regeneration of oral tissues, with particular reference to periodontal tissues. The main research lines include the design, functionalization, and characterization of three-dimensional scaffolds and micro- and nano-structured implant surfaces, aimed at improving osseointegration and the regeneration of both hard and soft tissues of the oral cavity. A central area of scientific work concerns the study of interactions between biomaterials and cells, with a focus on the molecular and cellular mechanisms regulating cell adhesion, proliferation, differentiation, and polarization, as well as the modulation of the inflammatory response. Particular attention is given to the role of material topography and physicochemical properties in influencing the biological response, including interactions with the tissue microenvironment and biological fluids. The research adopts a strongly translational approach, integrating in vitro studies, preclinical models, and clinical trials, also through the analysis of biological samples derived from patients, in compliance with current ethical regulations. The ultimate goal is the development of advanced and personalized therapeutic strategies for the treatment of oral and dental diseases, with particular emphasis on applications in implantology and periodontology.

Publications

Research projects

  • Reduced impact in the use of antibiotics for dental implant insertion: evaluation of antimicrobial peptide activity at the biomaterial/cell interface – a preliminary study

    Managers: Ghezzi Benedetta; Giovati Laura; Lumetti Simone; Manfredi Maddalena; Mergoni Giovanni

  • Three-dimensional silk fibroin bioactive composite scaffolds functionalized with aptamers for bone regeneration: from bench to pre-clinical testing

    Manager: Ghezzi Benedetta

  • LONGITUDINAL STUDY WITH IN VIVO MICRO-CT ON THE EFFICACY OF A 3D-PRINTED BIOMATERIAL FOR BONE REGENERATION

    Manager: Ghezzi Benedetta

  • INFLUENCE OF IMPLANTABLE SURFACES MICRO/NANO-TOPOGRAPHY AND HYDROPHILICITY ON THE MODULATION OF HUMAN MACROPHAGE M1/M2 POLARIZATION

    Managers: Ghezzi Benedetta; Lumetti Simone