Personale docente

CURRICULUM VITAE

DR. FABIO SONVICO

Data e luogo di nascita : 9 Dicembre 1974, Como
Cittadinanza : Italiana

POSIZIONI RICOPERTE
2015-oggi
Professore Associato presso il Dipartimento di Scienze degli Alimenti e del Farmaco dell'Università di Parma.
2012
Assunto come Senior Lecturer presso la School of Pharmacy della University of Technology Sydney, Australia
2005
Assegnatario di un posto di ricercatore universitario, settore scientifico/disciplinare CHIM/09, presso la Facoltà di Farmacia dell'Università degli Studi di Parma
2004
Ricercatore a contratto presso l’Unità di Ricerca di Parma at the National Institute for the Physics of the Matter (INFM), Research Unit of Parma, on the project: “Development of biopolymeric nanosystems suitable for the controlled delivery of drugs”

ISTRUZIONE
2003
Dottorato Francese in Tecnologie Pharmaceutique et Physico-chimie
Dottorato Italiano in Biofarmaceutica e Farmacocinetica
Assegnatario di una borsa di Dottorato dell’Associazione Francese per la Ricerca sul Cancro (ARC)
2000
Università degli Studi di Parma - Université de Paris Sud
Dottorato di ricerca in Biofarmaceutica e Farmacocinetica XV ciclo
Progetto in cotutela Italia-Francia dal titolo:
“Nanoparticelle metalliche funzionalizzate per il trattamento selettivo di tumori solidi”
Responsabili Prof. P.Colombo, Prof. P.Couvreur
1994 – 1999
Università degli Studi di Pavia
Laurea in Chimica e Tecnologia Farmaceutiche
Tesi, svolta presso la BAYER S.p.A., dal titolo:
“Applicazioni della Near Infra Red Spectroscopy al controllo qualità di forme farmaceutiche solide”
Relatrice Prof.ssa C.Caramella, Corelatore Dott. A.Schiavi (BAYER)
1994-1999 Alunno Collegio Borromeo di Pavia (Borsa C.Angelini)
1988-1993 Liceo Classico “T.Gallio”, Como

ESPERIENZE PROFESSONALI

Marzo-Luglio 1999 BAYER S.p.A. - Garbagnate milanese (MI)
Stagista presso il reparto PH-Quality Assurance
Responsabile della revisione e della presentazione dei dati analitici dell’anno 1998.

FORMAZIONI ULTERIORI
2017
ULLA Summer School - Organizzatore di una giornata di corso su “Nanomedicine for skin and mucosal application: local and systemic delivery” (Leuven, Belgium)
2013
The Woolcock Think Tank 2013, Sydney, Australia.
2012
6th Alzheimer & Parkinson’s Disease Symposium, Brain and Mind Institute, Camperdown, NSW, Australia
2011
ULLA Summer School - Organizzatore di una giornata di corso su “Site-specific drug delivery to the GI tract” (Parma, Italy)
Partecipazione al Workshop “Novel pharmaceutical technologies: from university labs to the pharma industries”, Parma, Italy
Seminar “Innovative Drug Delivery Systems” Basel, Switzerland
2010
Organizzatore del Congresso “Lactose as carrier for inhalation products”, Parma, Italy
2009
Workshop “Giornata di studio con aggiornamento regolatorio per studi clinici di Fase 1” I.P.A.S., Ligornetto, Switzerland
Workshop on “Quality by Design: Theory and tools made easy” University of Parma, Italy
2007
Workshop on Bioencapsulation and COST865 meeting, Lisbon, Portugal
2006
Aitun, AAPS Italian Student Chapter Workshop, “Pharmaceutical nanotechnology” – Università di Ferrara, Italy
2005
CRS Italian Chapter Workshop “Controlled release of oral therapeutics” – Università degli Studi di Pavia, Italia
2004
Corso Socrates “Innovative therapeutics: from molecules to medicines” – Università degli Studi di Parma, Italia
2003
3a Scuola di Dottorato su “Polimeri d’interesse farmaceutico” – Università della Calabria, Arcavacata di Rende, Italia
2003
Workshop “Nanohybrids” – Carry Le Rouet, Francia
2002
4th International Intensive Course and Workshop on Cell Culture and in vitro Models for Drug Absorption and Delivery – Saarland Universitat, Saarbrucken, Germania
2001
1st Socrates Course on Innovative therapeutics: from molecules to drug – Université de Paris Sud, Parigi, Francia

CONOSCENZE LINGUISTICHE

Inglese: conoscenza lingua scritta e orale buona.
Francese: ottima conoscenza della lingua scritta e orale.
Tedesco: conoscenza delle basi della lingua.
Spagnolo: conoscenza delle basi della lingua.

PARTECIPAZIONE A CONGRESSI

PUBBLICAZIONI SU PROCEEDINGS
1) Jimenez-Kairuz A., Bettini R., Sonvico F., Colombo P.
A new gastroretentive dosage form: floating Dome Matrix. Formulation and in vitro release studies of riboflavin.
The AAPS Journal. 2005; 7(S2), 1650.
2005 AAPS Annual Meeting, 6-10 November 2005, Nashville, USA

2) Como C., SonvicoF., Rossi A., Corradini E., Colombo P.
Influence of tamoxifen citrate loading on lecithin/chitosan nanoparticles
The AAPS Journal. 2006; 8(S2) 2740.
2006 AAPS Annual Meeting, October 29 - November 2, 2006, San Antonio, USA

3) Losi E., Jimenez-Kairuz A., Strusi O.L., Sonvico F., Colombo G., Bettini R., Colombo P.
Dome Matrix® technology : effect of drug solubility on release kinetics of swellable delivery modules
The AAPS Journal. 2006; 8(S2) 1625.
2006 AAPS Annual Meeting, October 29 - November 2, 2006, San Antonio, USA

4) Colombo G., Gallina L., Sonvico F., Colombo P., Bortolotti F., Menegatti E., Scatturin A., Scagliarini A.
Biohadesive sucralfate gel based suspension containing cidofovir for spray treatment of viral infections in lamb and sheep
The AAPS Journal. 2006; 8(S2) 2029.
2006 AAPS Annual Meeting, October 29 - November 2, 2006, San Antonio, USA

5) Rossi A., Colombo P., Sonvico F., Colombo G., Buttini F., Russo P.
Agglomerates of morphine microcrystals for nasal or buccal admnistration
The AAPS Journal. 2006; 8(S2) 1359.
2006 AAPS Annual Meeting, October 29 - November 2, 2006, San Antonio, USA

6) Colombo P., Rossi A., Russo P., Sonvico F., Colombo G., Buttini F.
Nasal powders of morphine microcrystal agglomerates
in Respiratory Drug Delivery X - Biological, Pharmaceutical, Clinical and Regulatory Issues Relating to Optimized Drug Delivery by Aerosol, Davis Healthcare International Publishing, River Grove, IL (USA), pp. 885-887 (2006)
ISBN: 1-930114-97-4
Respiratory Drug Delivery X, 23 – 27 April 2006, Boca Raton, USA

7) Colombo G., Russo P., Sonvico F., Ferraro, L., Bortolotti F.
Soft chimera agglomerates for desmopression nasal administration : an in vitro and in vivo study
Acta Pharmaceutica Sciencia. 2007; 29(S) 17.
The 5th International Postgraduate Research Symposium on Pharmaceutics IPORSIP – 2007, September 13-15, 2007, Istanbul, Turkey

8) Sonvico F., Colombo G., Gallina L., Bortolotti F., Colombo P., Menegatti E., Scagliarini A.
Use of Sucralfate Gel as a Vehicle for Topical Administration of the Antiviral Drug Cidofovir
The AAPS Journal. 2007; 9(S2), 1881.
2007 AAPS Annual Meeting, November 11-15, 2007, San Diego, USA

9) Buttini F., Vitale A., Rossi A., Sonvico F., Colombo P.
High Respirable Insulin Dry Powder for Pulmonary Administration
The AAPS Journal. 2007; 9(S2), 1905.
2007 AAPS Annual Meeting, November 11-15, 2007, San Diego, USA

10) Raffin R., Colombo P., Sonvico F., Rossi A., Pohlmann A., Gutierrez S.
Preparation and Characterization of a Pantoprazole New Drug Delivery System for Oral Administration Based on Soft Agglomerates
The AAPS Journal. 2007; 9(S2), 782.
2007 AAPS Annual Meeting, November 11-15, 2007, San Diego, USA

11) Strusi O. L., Sonvico F., Rossi A., Bettini R., Majori G., Colombo P.
Clindamycin-Artesunate Combined Multi-Kinetics Drug Delivery System for Malaria Therapy
The AAPS Journal. 2007; 9(S2), 2015.
2007 AAPS Annual Meeting, November 11-15, 2007, San Diego, USA

12) Como C., Sonvico F., Rossi A., Corradini E., Colombo P.
Lecithin/Chitosan Based Nanosystem for Tamoxifen Citrate Oral Delivery
The AAPS Journal. 2007; 9(S2), 757.
2007 AAPS Annual Meeting, November 11-15, 2007, San Diego, USA

13) Colombo G., Russo P., Sonvico F., Hesse E., Ferraro, L., Dalpiaz A., Bortolotti F.
In vitro and in vivo study of a desmopressin nasal powder
in RDD Europe 2007 - Respiratory Drug Delivery, Davis Healthcare International Publishing, River Grove, IL (USA), pp. 345-348 (2007)
ISBN: 1-933722-07-X
RDD Europe 2007, April 17-20, 2007, Paris, France

14) Ampollini L., Sonvico F., Bilancia R., Cavazzoni A., Barbieri S., Petronini P.G., Cantoni A.M., Fusari A., Rusca M., Carbognani P.
Intrapleural adjuvant treatment of mesothelioma: the combination of cisplatin- pemetrexed in a rat tumor model: a preliminary study
Interactive Cardiovascular and Thoracic Surgery. 2009; 9(S1), S1.
17th European Conference on General Thoracic Society, 31 May - 3 June 2009, Krakow, Poland

15) Miozzi M., Colombo P., Sonvico F., Buttini F.
Novel ciprofloxacin dry powders for pulmonary administration
The AAPS Journal. 2009; 11(S2), 897.
2009 AAPS Annual Meeting, Los Angeles, USA, 8-12 November 2009.

16) Conti C., Bardini B., Colombo P., Scarpignato C., Sonvico F., Rossi A.
Assembled delivery modules for clarithromycin release in Helicobacter Pylori therapy
The AAPS Journal. 2009; 11(S2), 3104.
2009 AAPS Annual Meeting, Los Angeles, USA, 8-12 November 2009.

17) Ampollini L., Sonvico F., Bilancia R., Cavazzoni A., Barbieri S., Petronini P.G., Cantoni A.M., Fusari A., Rusca M., Carbognani P.
Intrapleural adjuvant treatment of mesothelioma the combination of cisplatin- pemetrexed in a rat tumor model
Interactive Cardiovascular and Thoracic Surgery. 2010; 10(S1), S22.
18th European Conference on General Thoracic Society, 30 May - 2 June 2010, Valladolid, Spain

18) Barbieri S., Savi R., Sonvico F., Mazzaferro S., Bouchemal K., Ponchel G., Colombo P.
Tamoxifen loaded auto-assembled nanoparticles: cytotoxicity and intestinal permeability
The AAPS Journal. 2010; 12(S2), R6105.
2010 FIP Pharmaceutical Sciences World Congress, AAPS Meeting 2010, New Orleans, USA, 14-18 November 2010.

19) Galligioni V., Scagliarini A., Lorenzini L., Giuliani A., Zironi E., Pagliuca G., Calzà L., Colombo P., Sonvico F., Menegatti E., Colombo G.
Nose-to-brain delivery of ribavirin (RBV) for the treatment of viral encephalitis
The AAPS Journal. 2010; 12(S2), M1067.
2010 FIP Pharmaceutical Sciences World Congress, AAPS Meeting 2010, New Orleans, USA, 14-18 November 2010.

20) Buttini F., Cuoghi E., Miozzi M., Rossi A., Sonvico F., Colombo P.
Insulin Spray-Dried Powder and Smoothed Lactose: A New Formulation Strategy for Nasal and Pulmonary Delivery in Respiratory Drug Delivery 2012 (2012), Vol 3, pp 835-840. ISBN: 1-933722-59-2.
Respiratory Drug Delivery 2012, Phoenix, USA, 13-17 May 2012.

21) Sonvico F, Ampollini L, Carbognani P, Colombo P
Polymer films for the locoregional delivery of anticancer drugs in lung tumors
Pharm Anal Acta. 2013; 4(2), 63.
3rd International Conference and Exhibition on Pharmaceutics & Novel Drug Delivery Systems, Chicago/Northbrook (USA), 8-10 April 2013

22) Pozzoli M., Sonvico F. , Smith T., Zhu B., Traini D., Young P.M.
Evaluation OF PARTICLE SIZE DISTRIBUTION OF A COMMERCIAL NASAL POWDER DRUG DELIVERY DEVICE
J Aerosol Med Pulmo Drug Deliv (2104) 127(6):A7-A8.
ISAM and Woolcock 2014 Joint Conference and Workshop
Translating Advances in Understanding Lung Disease into Innovative Inhaled Therapeutics
Sydney, Australia, September 25–26, 2014

23) Pozzoli M., Sonvico F., Ong H.X., Traini D., Bebawy M., Young P.M.
Optimization of RPMI 2650 Cells as a Model for Nasal Mucosa
in Respiratory Drug Delivery 2014 (2014), Vol 3, pp 739-742. ISBN: 1-933722-79-7.
Respiratory Drug Delivery 2014, Fajardo, Puerto Rico, 4-8 May 2014.

24) Balducci A.G., Belotti S., Zhu B., Di Cuia M., Frascio D., Sonvico F., Bettini R., Colombo P., Buttini F.
Influence of Sodium Stearate on Amikacin Dry Powder Inhaler for the Treatment of Cystic Fibrosis Patients with Pseudomonas Aeruginosa Lung Infections
in Respiratory Drug Delivery Europe 2015 (2015), Vol 2, pp 507-510.
ISBN: 1-933722-79-7.
Respiratory Drug Delivery Europe 2015, Nice, France, 5-8 May 2015.

25) Pozzoli M., Cattaneo S., Zhu B., Traini D., Young P.M., Sonvico F.
Validation of a Novel Apparatus for Deposition Studies of Nasal Products
in Respiratory Drug Delivery Europe 2015 (2015), Vol 2, pp 537-541.
ISBN: 1-933722-79-7.
Respiratory Drug Delivery Europe 2015, Nice, France, 5-8 May 2015

26) Pozzoli M., Onog H.X., Sonvico F., Young P.M., Traini D.
Transport of Beclometasone Dipropionate across RPMI 2650 Model of Nasal Epithelium: Evaluation of Two Different Approaches to Drug Delivery In Respiratory Drug Delivery Europe 2016 (2016), Vol 3, pp 607-610. ISBN: 1-933722-96-7.

27) Sonvico F., Ampollini L., Carbognani P., Colombo P.
Development of an orphan drug medicinal product for the treatment of malignant mesothelioma
Acta Pharmaceutica Hungarica, (2017) 87 (3-4) 117
Book of Abstracts - 7th BBBB International congress on Pharmaceutical Sciences, Balatonfüred, 5-7 October 2017

28) Sonvico F., Rizzi A., Rossi A., Motta S., Cavatorta F., Santi P., Deriu A., Colombo P.
Progesterone loading in lecithin/chitosan nanoparticles for transmucosal delivery
The AAPS Journal. 2005; 7(S2), 1325.
2005 AAPS Annual Meeting, 6-10 November 2005, Nashville, USA

29) Russo P. Colombo P. Bettini R. Sonvico F. Buttini F. Chimeral agglomerates of microparticles for nasal administration of analgesic powders
in Respiratory Drug Delivery IX - Biological, Pharmaceutical, Clinical and Regulatory Issues Relating to Optimized Drug Delivery by Aerosol, Davis Healthcare International Publishing, River Grove, IL (USA), pp. 817-820 (2004)
ISBN: 1-930114-65-6
Respiratory Drug Delivery IX, 25-29 April 2004, Palm Desert, USA

30) Cagnani A., Sonvico F., Colombo P., Bettini R., Alonso M.J., Colombo G., Rossi A.
Chimerical agglomerates of lecithin/chitosan nanoparticles for powder nasal delivery
The AAPS Journal. 2004; 6(S1), 1190.
2004 AAPS Annual Meeting, 7-11 November 2004, Baltimore, USA.

31) Sonvico F., Mornet S., Dubernet C., Appel M., Chacun H., Jaillard D., Degrouard J., Hoebecke J., Duguet E., Colombo P., Couvreur P.
Folate targeted nanohybrids for the treatment of solid tumors
The AAPS Journal. 2003; 5(S1), 796.
AAPS 2003 Annual meeting, 26-30 October 2003, Salt Lake City, USA.

32) Caliceti P., Salmaso S., Carofiglio T., Fornasier R., Sonvico F., Couvreur P., Hoebeke J.
New cyclodextrin bioconjugates for active drug targeting
Controlled Release Society 30th Annual Meeting, Glasgow, Scotland, 19 – 23 July 2003

COMUNICAZIONI A CONGRESSO IN FORMA DI POSTER

Romana B., Mason A.F., Thordarson P., Sonvico F., Prestidge C.A.
Hybrid nanovectors for oral delivery of poorly water soluble drugs
6th International Nanomedicine Conference, 6 - 8 July 2015, Crowne Plaza Hotel at Coogee Beach, Sydney (Australia)

Pozzoli M., Sonvico F., Smith T., Zhu B., Traini D., Young P.M.
Evaluation of particle size distribution of a commercial nasal powder drug delivery device.
ISAM & Woolcock 2014, 25-26 September 2014, Woolcock Medical Institute, Sydney (Australia)

Sonvico F, Garrastazu G., Batger M. Simvastatin-loaded chitosan nanocapsules for an innovative administration of statins. 5th FIP Pharmaceutical Sciences World Congress (PSWC). 13- 16 April 2014, Melbourne (Australia).

Colombo G, Bortolotti F, Sonvico F, Balducci AG, Rossi A, Colombo P, Buttini F. In vitro transport studies across excised nasal mucosa for three drug candidates to nose-to-brain delivery. 5th FIP Pharmaceutical Sciences World Congress (PSWC). 13- 16 April 2014, Melbourne (Australia).

Pozzoli M., Sonvico F., Smith T., Zhu B., Traini D., Young P.M.
Evaluation of particle size distribution of a commercial nasal powder drug delivery device.
Drug Delivery Australia 2013, 24-25 October 2013, Woolcock Medical Institute, Sydney

Sonvico F., Coleman V., Traini D., Young P.M.
TG-IR analysis of decomposition products of salbutamol sulfate
Drug Delivery Australia 2013, 24-25 October 2013, Woolcock Medical Institute, Sydney

Barbieri S., Sonvico F., Como C., Colombo P., Zani F., Buttini F., Bettini R., Rossi
A., Colombo G.
Lecithin/chitosan autoassembled nanoparticles for oral administration of tamoxifen citrate.
19th International Symposium on Microencapsulation, 9-11 September 2013, Pamplona, Spain

Ahmad Fisol F.A., Sonvico F., Colombo P., Al-Ashraf Abdullah A., Abd Wahab H., Abd Maijid M.I.
Production and development op poly(3HB-co-4HB) nano particles for the delivery of docetaxel
Formula VII, 1-4 July 2013, Universite’ de Haute Alsace, Mulhouse, France

Mercuri S., Strusi O.L., Sonvico F., Rossi A., Colombo P.
Dome Matrix modular assembled system for the treatment of Parkinson’s disease
2nd Conference Innovation in Drug Delivery: from preformulation to the development through innovative evaluation process, Aix-en-Provence, 3-6 October 2010

Senyigit T., Sonvico F., Barbieri S., Santi P., Colombo P., Ozer O.
In vivo assessmen of clobetasol propionate loaded lecithin-chitosan nanoparticles for topical use
2nd Conference Innovation in Drug Delivery: from preformulation to the development through innovative evaluation process, Aix-en-Provence, 3-6 October 2010

Marin L., Sonvico F., Massimo G., Colombo P., Buttini F.
Flowability and respirability of insulin dry powder blends for pulmonary administration
Lactose as a carrier for inhalation products, 26-28 September 2010, Parma, Italy

Colombo G., Rimessi A., De Corcelli A., Menegatti E., Bortolotti F., Sonvico F., Colombo P. Combination of alginate and cells for skin regeneration
PharmaTech 2010 - International Conference and Exhibition on Pharmaceutical, Nutraceutical and Cosmeceutical Technology: Formulation and Applications, 25-26 May 2010, KLCC, Kuala Lumpur, Malaysia

Strusi O.L., Sonvico F., Barata P., Mercuri S., Colombo G., Buttini F., Bettini R., Colombo P.
Multi-kinetics and site specific oral delivery system of artesunate-clindamycin c ombination for malaria treatment
7th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 8-11 March 2010, Valletta, Malta

Miozzi M., Sonvico F., Colombo P., Buttini F.
Construction of ciprofloxacin dy microparticles for lung infection treatment
7th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 8-11 March 2010, Valletta, Malta - Abstract 68

Senyigit T., Sonvico F., Barbieri S., Ozer O., Santi P., Colombo P.
Preparation and characterization of clobetasol-17-propionate loaded lecithin- chitosan nanoparticles for topical use
7th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 8-11 March 2010, Valletta, Malta - Abstract 136

Colombo G., Scagliarini A., Gallina L., Bortolotti F., Rossi A., Colombo P., Menegatti E., Sonvico F.
Therapeutic paint for simultaneous delivery of sucralfate gel and cidofovir in the treatment of veterinary viral skin infections
17th International Symposium on Microincapsulation, 29 September - 1 October 2009, Nagoya, Japan

Balducci A.G., Colombo P., Cavallari C., Rodriguez L., Sonvico F., Rossi A.
Gastro-resistant multiparticulate dosage form for mesalazine colon delivery in paediatric patients
17th International Symposium on Microincapsulation, 29 September - 1 October 2009, Nagoya, Japan

Sonvico F., Ampollini L., Barbieri S., Marcotti E., Colombo G., Carbognani P., Colombo P.
Polysaccharide films loaded with anticancer drugs for locoregional therapy of malignant pleural mesothelioma
17th International Symposium on Microincapsulation, 29 September - 1 October 2009, Nagoya, Japan

Raffin R., Haas S.E., Colomé L.M., Hoffmeister C.R.D., Colombo P., Sonvico F., Colmè L.M., Natalini C.C., Pohlmann A., Dalla Costa T., Guterres, S.
Pharmacokinetics evaluation of soft agglomerates containing pantoprazole-loaded microparticles in dogs
36th Annual Meeting & Exposition of the Controlled Release Society, 18-22 July 2009, Copenhagen, Danemark

Raffin R., Colomé l., Hoffmeister C., Dalla Costa T., Pohlmann A., Colombo P., Sonvico F., Rossi A., Colmè l., Guterres, S.
Soft agglomerates of pantoprazole gastro-resistant microparticles for oral administration: pharmacokinetics evaluation
2nd PharmSciFair, 8-12 June 2009, Nice, France

Conti C., Rossi A., Sonvico F., Scarpignato C., Colombo P.
Influence of HPMC polymer content on clarithromycin release from module assembled system
2nd PharmSciFair, 8-12 June 2009, Nice, France

Barbieri S., Marcotti E., Sonvico F., Rossi A., Colombo P.
Tamoxifen loaded autoassembled nanoparticles: cellular uptake and enzymatic degradation
2nd PharmSciFair, 8-12 June 2009, Nice, France

Colombo G., Gallina L., Rossi A., Colombo P., Bortolotti F., Menegatti E., Scagliarini A., Sonvico F.
Study of a sucralfate gel-based therapeutic paint for antiviral drug topcla application by spraying
XX Simposio A.D.R.I.T.E.L.F., 10-13 September 2009, Cagliari, Italy

Strusi O.L., Mercuri S., Sonvico F., Bettini R., Colombo P., Heng P.W.
Influence of granule dimension on the mechanical characteristics of Dome Matrix modules
2nd PharmSciFair, 8-12 June 2009, Nice, France

Sonvico F., Colombo P., Scagliarini A., Gallina L., Colombo G.
Spray therapeutic paint for topical treatment of orf virus skin infections in breeding sheep
2nd PharmSciFair, 8-12 June 2009, Nice, France

Ampollini L., Sonvico F., Bilancia R., Barbieri S., Stavroulias D., Cavazzoni A., Petronini P.G., Cantoni A.M., Rusca M., Carbognani P.
Intrapleural polymeric devices containing cisplatin for malignant pleural mesothelioma in a rat tumor model: a preliminary study
17th European Conference on General Thoracic Surgery, 31 May - 3 June 2009, Krakow, Poland

Coelho P., Santos D., Bettini R., Colombo P., Sonvico F., Strusi O.L.
Development of a ranitidine controlled release gastroretentive oral dosage form
68th International Congress of FIP - Reengineering Pharmacy Practice in a Changing World, 29 August - 4 September 2008, Basel, Switzerland

Sonvico F., Sacchetti G., Gussago F., Barbieri S., Rossi A., Colombo P., Carbognani P.
Polysaccahrdic films loaded with cisplatin for the locoregional therapy of pleural malignant mesothelioma
6th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, April 7-10, 2008, Barcelona, Spain

Rossi A., De Haan B., Sonvico F., De Vos p., Colombo P.
Study of human protein adsorption onto sodium alginate/poly-L-lysine beads by micro fourier transformed infrared spectroscopy
6th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, April 7-10, 2008, Barcelona, Spain

Colombo G., Russo P., Sonvico F., Hesse E., Ferraro L., Bortolotti F., Colombo P.
Desmopressin dry powder for nasal administration
Innovation in drug delivery : from biomaterials to devices, September 30 – October 3, 2007, Naples, Italy

Sonvico F., Barbieri S., Rossi A., Gerelli Y., Deriu A., Colombo P., Colombo G.
Progesterone-loaded lechitin/chitosan/isopropyl myristate nanoparticles for transmucosal delivery
Innovation in drug delivery : from biomaterials to devices, September 30 – October 3, 2007, Naples, Italy

Coelho P., Strusi L., Sonvico F., Bettini R, Colombo P., Ribeiro L., Santos D., Sousa Lobo, J.M., Ferreira D.
Gastric retention and bioavailability determination of ranitidine immediate and controlled release Dome Matrix formulation in dogs
Innovation in drug delivery : from biomaterials to devices, September 30 – October 3, 2007, Naples, Italy

C. Como, F. Sonvico, A. Rossi, E. Corradini and P. Colombo
A new nanosystem for tamoxifen citrate oral delivery
16th International Symposium on Microencapsulation, September 9 -12, 2007, Lexington, Kentucky, USA
Colombo G., Bortolotti F., Colombo P., Menegatti E., Sonvico F.,
Soft agglomerates containing microincapsulated levothyroxine for buccal oral delivery
16th International Symposium on Microencapsulation, September 9 - 12, 2007, Lexington, USA

Parlati C., Buttini F., Sonvico F., Colombo P.
Innovative tobramycin dry powder for pulmonary administration
16th International Symposium on Microencapsulation, September 9 - 12, 2007, Lexington, USA

Deriu A., Gerelli Y., Como C., Sonvico F., Di Bari M.T., Colombo P., May R.
Neutron investigation of the structure and organization of phospholipid/polysaccharide nanoparticles
4th European Conference on Neutron Scattering, 25-29 June 2007, Lund, Sweden.

Deriu A., Chiapponi C., Di Bari M.T., Sonvico F., Santi P., Nicoli S., Padula C.
Water diffusivity in PVA-based transdermal patches
4th European Conference on Neutron Scattering, 25-29 June 2007, Lund, Sweden

Coelho P., Bettini R., Colombo P., Sonvico F., Strusi L., Sosa Lobo J.M., Delfim S., Ferreira D., Soares M.E., Ribeiro L.
“Gastric retention and bioavailability determination of ranitidine Dome Matrix formulations in dogs”
Young Pharmaceutical Scientists meet in Amsterdam, Pre-satellite meeting of the 3rd Pharmaceutical Science World Congress, 20-21 April 2007, Amsterdam, The Netherlands

Coelho P., Bettini R., Colombo P., Sonvico F., Strusi L., Oliveira A., Sosa Lobo J.M., Delfim S., Ferreira D.
Gamma scintigraphy evaluation of floating Dome matrix gastric residence in humans
3rd Pharmaceutical Science World Congress, 22-25 April 2007, Amsterdam, The Netherlands

Barata P., Colombo P., Bettini R., Sonvico F., Strusi L., Sousa Lobo J.M., Delfim S., Ferreira D.
Plataforma Dome Matrix : un sistema farmaceutico inovador
Congresso Nacional dos Farmaceuticos, 8-10 March 2007, Lisbon, Portugal

Gallina L., Colombo G., Sonvico F., Dal Pozzo F., Borlotti F. Menegatti E., Scatturin A., Colombo P., Scagliarini A.
Cidofovir spray formulation for the topical treatment of orf virus infected sheep
8th Congress of Chemotherapy and Infection (EEC8) – 4th European Conference on Viral Diseases (ConVir 4), 26-28 October 2006, Budapest, Hungary

Sonvico F., Barbieri S., Rossi A., Motta S., Bettini R., Deriu A., Colombo P.
Lecithin/chitosan self-organized nanoparticles as drug carriers for lipophilic drugs
XIV International Workshop on Bioencapsulation & COST 865 Meeting, 5-7 October 2006, Lausanne, Switzerland

Sonvico F., Bove L., Deriu A., Cavatorta F., Di Bari M.T., Albanese G.
Mean square hydrogen fluctuations in chitosan/lecithinnanoparticles from elastic neutron scattering experiments
International Conference on Neutron Scattering 2005, 27 November – 2 December 2005, Sydney, Australia

Sonvico F., Deriu A., Di Bari M.T., Albanese G., Cavatorta F., Calandrini V., May R.
Small angle scattering investigation of chitosan/lecithin nanoparticles, potential carriers for drug delivery
International Conference on Neutron Scattering 2005, 27 November – 2 December 2005, Sydney, Australia

Jimenez-Kairuz A., Bettini R., Sonvico F., Como C., Strusi O. L., Colombo P.
Riboflavin release from hydrophilic matrices using Dome Matrix®
technology
2nd EUFEPS Conference on Optimising Drug Delivery and Formulation : Evaluation of Drug Delivery Systems Issues and Perspectives, 20-23 November 2005, Versailles, France

Sonvico F., Rossi A., Motta S., Cavatorta F., Bettini R., Deriu A., Colombo P.
Lecithin-chitosan nanoparticles for the transmucosal delivery of progesterone via chimerical agglomerates
15th Symposium on Microincapsulation, 18-21 September 2005, Parma, Italy

Colombo G., Buttini F., Sonvico F., Colombo P., Russo P., Scatturin A., Menegatti E.
Respiratory drug delivery
International school on advanced material science and technology, 6-9 September 2005, Jesi, Italy

Sonvico F., Mornet S., Dubernet C., Appel M., Chacun H., Duguet E., Colombo P., Couvreur P.
In vitro uptake of folate targeted nanohybrids in a folate receptor expressing cellular model
International Conference on Drug Delivery and Pharmaceutical Technology, 10-12 May 2004, Seville, Spain

Sonvico F., Mornet S., Vasseur S., Appel M., Chacun H., Dubernet C., Colombo P., Duguet E., Couvreur P.
In vitro uptake of folate-targeted VUSPIO in a folate-receptor expressing model
5th Magnetic Carrier Meeting, 20-22 May 2003, Lyon, France

Sonvico F., Salmaso S., Caliceti P., Dubernet C., Colombo P., Couvreur P.
Evaluation in vitro d’un nouveau vecteur conjugué à l’acide folique pour le ciblage de tumeurs solides,
XVIIièmes Journées scientifiques du G.T.R.V., 12-13 December 2002, Paris, France

X.Jurvilliers, R Schneider, Y Fort, S Begin-Colin, J.M. Dubois, F.Sonvico, C.Dubernet, P.Couvreur, O. Tillement
Functionalised nanoparticles for medicinal applications,
XXXV I.C.C.C., 21-26 July 2002, Heidelberg, Germany

Sonvico F., Dubernet C.,Appel M., Chacun H., Jurvilliers X., Schneider R., Fort Y., Tillement O., Colombo P., Couvreur P.
Folate linked metallic nanoparticles targeting tumor cells,
4th World Pharmaceutical Meeting ADRITELF/APGI/APV, 8-11 April 2002, Florence, Italy

Sonvico F., Dubernet C., Appel M., Chacun H., Colombo P., Couvreur P.
Développement d'un modèle in vitro de cellules tumorales hyperexprimant le récepteur à l'acide folique en vue de l'étude de la capture spécifique de vecteurs pilotés ,
XVIièmes Journées scientifiques du G.T.R.V., 9-10 December 2001, Lyon, France

PRESENTAZIONI ORALI

Sonvico F., Ampollini L., Rossi A., Carbognani P., Colombo P.
Development of an orphan drug medicinal product for the treatment of malignant mesothelioma
7th BBBB International congress on Pharmaceutical Sciences, Balatonfüred, 5-7 October 2017

Sonvico F.
Pharmaceutical nanotechnology: Which opportunities in non-parenteral administration routes?
Invited Speaker - 8th Meeting of the Pharmaceutical Science Graduate Program, 14-15 December 2016, Porto Alegre, Brazil

Sonvico F., Deriu A., Colombo P.,
Biodegradable Nanoparticles: a Pharmaceutical Nanotechnology Platform for the Delivery of Poorly Soluble Drugs.
2nd Parma NanoDay, 3-4 December 2015, Parma, Italy

Sonvico F., Colombo P., Colombo G.
Biodegradable Lecithin/Chitosan Nanoparticles: a Pharmaceutical Nanotechnology Platform for the Delivery of Poorly Soluble Drugs.
NanotechITALY 2015, 25-27 November 2015, Bologna, Italy

Sonvico F., Ampollini L., Rossi A., Carbognani P., Colombo P.
Polymer films for the locoregional delivery of anticancer drugs in lung tumors.
Pharmaceutica 2013, 3rd International Conference and Exhibition on Pharmaceutics & Novel Drug Delivery Systems, 8-10 April 2013, Chicago, IL, USA

Sonvico F., Colombo G., Calza’ L., Scagliarini A.
Drug delivery to the brain
Drug Delivery Australia 2012, 6th Annual Meeting of the Australian Chapter of the Controlled Release Society, 26-27 November 2012, Melbourne, Australia

Sonvico F.
Prodotti combinati ed innovativi nei sistemi di rilascio dei farmaci antimalarici, 39 Congresso Nazionale Sociteta’ Italiana di Microbiologia, 3-6 October 2011, Riccione, Italy

Sonvico F., Dushi B.
Modular systems for controlled release of clindamycin/artesunate in adults
Workshop “Novel anti-malaria therapy in adults and children: application of controlled release technologies”, 1st June 2011, Università degli Studi di Parma, Parma, Italy

Sonvico F.
Polysaccharide films for loco-regional therapy of lung tumor
One day Seminar “Advances in drug delivery systems 2011”, 19 April 2011, Universiti Sains Malaysia/ Malaysian Society of Pharmaceutical Technology, Penang, Malaysia

Sonvico F.
Preparazioni solide orali per la somministrazione di farmaci combinati in una sola forma di dosaggio
Workshop “Next Generation Medicines”, 30 November 2010, Bologna

Sonvico F.
Polysaccharide films: a drug delivery patform for loco-regional therapy of malignat pleural mesothelioma
IMIG2010, 31 August - 2 September 2010, Kyoto, Japan

Sonvico F., Ampollini L., Rossi A., Carbognani P., Colombo P.
Cisplatin-loaded polymeric films for the intrapleural treatment of mlignant pleural mesothelioma
PharmaTech 2010 - International Conference and Exhibition on Pharmaceutical, Nutraceutical and Cosmeceutical Technology: Formulation and Applications, 25-26 May 2010, KLCC, Kuala Lumpur, Malaysia

Sonvico F.
Lecithin/chitosan nanosystems for the delivery of lipophilic drugs
One day seminar on “New advances in drug delivery systems”, 24 May 2010, Universiti Sains Malaysia, Penang, Malaysia

Sonvico F., Barbieri S., Ampollini L., Rossi A., Carbognani P., Colombo P.
Polysaccharide films loaded with cisplatin for lung mesothelioma loco-regional therapy
XX Simposio A.D.R.I.T.E.L.F., 10-13 September 2009, Cagliari, Italy

Barbieri S., Marcotti E., Sonvico F., Colombo P.
Chitosan/Lecithin autoassembled nanoparticles: a new carrier for oral delivery
of tamoxifen
9th International Conference of the European Chitin Society, 23-26 May 2009, Venice, Italy

Sonvico F., Como C., Barbieri S., Gereli Y., Deriu A., Colombo P.
Lecithin/chitosan nanosystems for tamoxifen oral deliery
Anticancer drug delivery: new perspectives in tumor targeting - Thematic workshop of Controlled Release Society Italian Chapter, 28-29 November 2008, Padua, Italy

Sonvico F., Como C., Barbieri S., Gereli Y., Deriu A., Colombo P.
Lecithin/chitosan nanosystems for the oral and transmucosal deliery of lipophilic drugs
14th International Pharmaceutical Technology Symposium, 6-10 September 2008, Antalya, Turkey

Sonvico F.
Pharmaceutical nanotechnology in tumor targeting
Advances in pharmaceutical technology : development of controlled release formulations and implement of new techniques, April 3, 2008, Madrid, Spain

Sonvico F., Colombo P., Como C.
“Nanoparticelle ottenute dall’interazione tra lecitina e chitosano per la veicolazione di farmaci lipofili”
47° Simposio AFI, 13-15 June 2007, Rimini, Italy

Colombo P., Sonvico F. , Strusi O.L.
“Dome Matrix(r) Technology”
Workshop on “Medicines and paper: what future together?”, 5 May 2006, Parma, Italy

Colombo P., Sonvico F., Losi E., Bettini R.
The geometrical approach for modulation of drug delivery from swallebale matrix tablets: the Dome Matrix technology
FMC Biopolymer - Controlled release Seminar/Tablet Tech, 25-26 May 2004, Brussels, Belgium

Sonvico F., Salmaso S., Caliceti P., Dubernet C., Colombo P., Couvreur P.
Evaluation in vitro d'un nouveau vecteur conjugué à l'acide folique pour le ciblage de tumeurs solides
Groupe Thématique de Recherche sur le Vecteurs - GTRV2002, 12-13 December 2002, Paris France

PUBBLICAZIONI SCIENTIFICHE SU RIVISTE INTERNAZIONALI

2004

1) Salmaso S., Semenzato A., Caliceti P., Hoebecke J., Sonvico F., Dubernet C., Couvreur P.
Specific anti-tumor targetable β-cyclodextrin-PEG-folate drug delivery system
Bioconjugate Chem 15, 997-1004 (2004)
doi: 10.1021/bc034186d

2) Russo P, Buttini F., Sonvico F., Bettini R., Massimo G., Sacchetti C., Colombo P., Santi P.
Chimeral agglomerates of microparticles for administration of caffeine nasal powders
J Drug Del Sci Tech, 14, 449-454 (2004)
doi: 10.1016/S1773-2247(04)50083-7

2005

3) Gainotti A., Losi E., Bettini R., Colombo P., Sonvico F., Baroni D., Santi P., Colombo G.
Effect of microwave drying and residual water content on the physico-chemical properties of sucralfate humid gel
Drug Dev Ind Pharm, 31, 645-652 (2005)
doi: 10.1080/03639040500216337

4) Sonvico F., Dubernet C., Colombo P., Couvreur P.
Metallic colloid nanotechnology: applications in diagnosis and therapeutics
Curr Pharm Des, 11(16), 2091-2105 (2005)

5) Del Gaudio P, Colombo P., Colombo G., Russo P., Sonvico F.
Mechanisms of formation and disintegration of alginate beads obtained by prilling
Int J Pharm, 302, 1-9 (2005)
doi: 10.1016/j.ijpharm.2005.05.041

6) Sonvico F., Dubernet C., Appel M., Chacun H., Colombo P., Couvreur P.
Establishment of an in vitro model expressing the folate receptor for the investigation of targeted delivery systems
J Drug Del Sci Tech, 15, 407-410 (2005)
doi: 10.1016/S1773-2247(05)50080-7

7) Sonvico F., Mornet S., Vasseur S., Dubernet C., Jaillard D., Degrouard J., Hoebecke J., Duguet E., Colombo P., Couvreur P. Folate-conjugated iron oxide nanoparticles for solid tumor targeting as potential specific magnetic hyperthermia mediators: synthesis, physicochemical characterization, and in vitro experiments. Bioconj Chem, 16, 1181-1188 (2005).
doi: 10.1021/bc050050z
Selected for the 25th Anniversary Collection by the Editor-in-Chief, Prof. Vincent Rotello (University of Massachusetts, USA).

8) Colombo P., Sonvico F.
Les formes pharmaceutiques du futur
J Pharm Bel, 60, 1-4 (2005)

2006

9) Gainotti A., Losi E., Colombo P., Sonvico F., Massimo G., Colombo G., Del Gaudio P.
The effect of residual water content on antacid properties of sucralfate gel dried by microwaves
AAPS PharmSciTech (on line) 7 : article 9 (2006)
doi: 10.1208/pt070109

10) Losi E., Bettini R., Santi P., Sonvico F., Colombo G., Lofthus K., Colombo P., Peppas N.A.
Assemblage of novel release modules for the development of adaptable drug delivery systems
J Control Rel, 111, 212-218 (2006)
doi: 10.1016/j.jconrel.2005.12.006

11) Sonvico F., Cagnani A., Rossi A., Motta S., Di Bari M.T., Cavatorta F., Alonso M.J., Deriu A., Colombo P.
Formation of self-organized nanoparticles by lecithin/chitosan ionic interaction
Int. J. Pharm., 314, 66-73 (2006)
doi: 10.1016/j.ijpharm.2006.06.036

12) Sonvico F., Di Bari M.T., Bove L., Deriu A., Cavatorta F., Albanese G.
Mean square hydrogen fluctuations in chitosan/lecithin nanoparticles from elastic neutron scattering experiments
Physica B, 385, 725–727 (2006)
doi: 10.1016/j.physb.2006.06.034

2007

13) Raffin R.P., Colombo P., Sonvico F., Polleto F.S., Colombo G., Rossi A., Polhmann A.R., Guterres S.S.
Soft agglomerates of pantoprazole gastro-resistant microparticles for oral administration and intestinal release
J Drug Del Sci Tech, 17, 407-413 (2007)
doi: 10.1016/S1773-2247(07)50081-X

2008

14) Di Bari M.T., Gerelli Y., Sonvico F., Deriu A., Cavatorta F., Albanese G., Colombo P. and Fernandez-Alonso F.
Dynamics of lipid–saccharide nanoparticles by quasielastic neutron scattering
Chem Phys, 345, 239-244 (2008)
doi:10.1016/j.chemphys.2007.08.006

15) Gerelli Y., Di Bari M.T., Deriu A., Cantù L., Colombo P., Como C., Motta S., Sonvico F., May R.
Structure and organization of phospholipid/polysaccharide nanoparticles
J Phys: Condens Matter, 20 (10), 104211 (8pp) (2008)
doi: 10.1088/0953-8984/20/10/104211

16) Strusi O.L., Sonvico F., Bettini R., Santi P., Colombo G., Barata P., Oliveira A., Santos D., Colombo P.
Module assemblage technology for floating systems: in vitro flotation and in vivo gastro-retention
J Control Release, 129 (2), 88-92 (2008)
doi: 10.1016/j.jconrel.2008.04.015

17) Natali F., Peters J., Russo D., Barbieri S., Chiapponi C., Cupane A., Deriu A., Di Bari M.T., Farhi E., Gerelli Y., Mariani P., Paciaroni A., Rivasseau C., Schirò G., Sonvico F.
IN13 Backscattering Spectrometer at ILL: Looking for Motions in Biological Macromolecules and Organisms
Neutron News, 19 (4), 14-18 (2008)
doi:10.1080/10448630802474083

18) Gerelli Y., Barbieri S., Di Bari M.T., Deriu A., Cantù L., Brocca P., Sonvico F., Colombo P., Motta S., May R.
Structure of self-organized multilayer nanoparticles for drug delivery
Langmuir, 24, 11378-11384 (2008)
doi: 10.1021/la801992t

2009

19) Colombo P., Sonvico F., Colombo G., Bettini R.
Novel Platforms for Oral Drug Delivery
Pharm Res, 26(3), 601-611 (2009)
doi: 10.1007/s11095-008-9803-0

20) Bortolotti F., Balducci A.G, Sonvico F., Russo P., Colombo G.
In vitro permeation of desmopressin across rabbit nasal mucosa from liquid nasal sprays: the enhancing effect of potassium sorbate.
Eur J Pharm Sci, 37, 36-42 (2009)
doi: 10.1016/j.eps.2008.12.015

21) Sonvico F., Colombo G., Gallina L., Bortolotti F., Rossi A., McInnes C.J., Massimo G., Colombo P., Scagliarini A.
Therapeutic paint of cidofovir/sucralfate gel combination topically administered by spraying for treatment of orf virus infections.
AAPS J, 11(2), 242-249 (2009)
doi: 10.1208/s12248-009-9101-8

22) Raffin R., Colombo P., Sonvico F., Rossi A., Jornada D.S., Pohlmann A.R., Guterres S.S.
Agglomerates containing pantoprazole microparticles: modulating the drug release.
AAPS PharmSciTech, 10(2), 335-345 (2009)
doi: 10.1208/s12249-009-9214-5

2010

23) Gerelli Y., Di Bari M.T., Barbieri S., Sonvico F., Colombo P., Natali F., Deriu A.
Flexibility and drug release features of lipid/saccharide nanoparticles
Soft Matter, 6, 685 – 691 (2010)
doi:10.1039/b916139b

24) Huynh T.T.N., Padois K., Sonvico F., Rossi A., Zani F., Pirot F., Doury J., Falson F.
Characterization of a polyurethane-based controlled release system for local delivery of chlorhexidine diacetate
Eur J Pharm Biopharm, 74, 255-264 (2010)
doi:10.1016/j.ejpb.2009.11.002

25) Raffin R., Colomé L.M, Hoffmeister C.R.D., Colombo P., Rossi A., Sonvico F., Colomé L.M., Natalini C.C., Polhmann A.R., Dalla Costa T., Guterres S.S.
Pharmacokinetics evaluation of soft agglomerates for prompt delivery of enteric pantoprazole-loaded microparticles
Eur J Pharm Biopharm, 74, 275-280 (2010)
doi:10.1016/j.ejpb.2009.11.015

26) Ampollini L., Sonvico F., Barocelli E., Cavazzoni A., Bilancia R., Mucchino C., Cantoni A.M., Carbognani P.
Intrapleural polymeric films containing cisplatin for malignant pleural mesothelioma in a rat tumour model: a preliminary study
Eur J Cardiothorac Surg, 37, 557-565 (2010)
doi: 10.1016/j.ejcts.2009.08.012

27) Senyigit T., Sonvico F., Barbieri S., Ozer O., Santi P., Colombo P.
Lecithin/chitosan nanoparticles of clobetasol-17-propionate capable of accumulation in pig skin
J Control Rel, 142, 368-373 (2010)
doi: 10.1016/j.jconrel.2009.11.013

28) Strusi O.L., Barata P., Traini D., Young P.M., Mercuri S., Colombo G., Sonvico F., Bettini R., Colombo P.
Artesunate-clindamycin multi-kinetics and site-specific oral delivery system for antimalaric combination products
J Control Rel, 146, 54-60 (2010)
doi: 10.1016/j.jconrel.2010.05.001

29) Padula C., Chiapponi C., Di Bari M.T., Deriu A., Sonvico F., Barbieri S., Ollivier J., Santi P.
Single layer transdermal film containing lidocaine: water and lidocaine mobility determined using neutron scattering
J Pharm Sci, 99, 4277-4284 (2010).
doi: 10.1002/jps.22152

2011

30) Wong T.W, Colombo G., Sonvico F.
Pectin matrix as oral drug delivery vehicle for colon cancer treatment
AAPS PharmSciTech, 12(1), 201-214 (2011)
doi: 10.1208/s12249-010-9564-z

31) Oliveira P.R., Sakis Bernardi L., Strusi O.L., Mercuri S., Segatto Silva M., Colombo P., Sonvico F.
Assembled modules technology for site-specific prolonged delivery of norfloxacin
Int J Pharm, 405, 90-96 (2011)
doi: 10.1016/j.ijpharm.2010.11.050

32) de Haan B.J., Rossi A., Faas M.M., Smelt M.J., Sonvico F., Colombo P., de Vos P.
Structural surface changes and inflammatory responses against alginate-based microcapsules after exposure to human peritoneal fluid.
J Biomed Mater Res A, 98(3), 394-403 (2011)
doi: 10.1002/jbm.a.33123.

33) Colombo G., Lorenzini L., Zironi E., Galligioni V., Sonvico F., Balducci A.G., Pagliuca G., Giuliani A., Calzà L., Scagliarini A.
Brain distribution of ribavirin after intranasal administration
Antiviral Res, 92 408–414 (2011)
doi:10.1016/j.antiviral.2011.09.012

2012

34) Buttini F., Colombo P., Rossi A., Sonvico F., Colombo G.
Particles and powders: Tools of innovation for non-invasive drug administration.
J Control Release, 161 (2), 693-702 (2012).
doi:10.1016/j.jconrel.2012.02.028

35) Scagliarini A., Bettini G., Savini F., Spadari A., Sonvico F., Balducci A.G., Calbucci S., Colombo G.
Treatment of equine sacroids
Vet Rec, 171, 330 (2012).
doi:10.1136/vr.e6506

36) Padois K., Bertholle V., Pirot F., Hyunh T.T., Rossi A., Colombo P., Falson F., Sonvico F.
Chlorhexidine salt-loaded polyurethane orthodontic chains: in vitro release and antibacterial activity studies.
AAPS PharmSciTech 13 (4), 1446-1450 (2012).
doi: 10.1208/s12249-012-9872-6.

2013

37) Balducci A.G., Ferraro L., Bortolotti F., Nastruzzi C., Colombo P., Sonvico F., Russo P., Colombo G.
Antidiuretic effect of desmopressin chimera agglomerates by nasal administration in rats
Int J Pharm 440, 154-160 (2013)
doi: 10.1016/j.ijpharm.2012.09.049

38) Tarabella G, Balducci AG, Coppedè N, Marasso S, D'Angelo P, Barbieri S, Cocuzza M, Colombo P, Sonvico F, Mosca R, Iannotta S
Liposome sensing and monitoring by organic electrochemical transistors integrated in microfluidics.
Biochim Biophys Acta 1830(9):4374-4380 (2013)
doi:10.1016/j.bbagen.2012.12.018.

39) Barbieri S., Sonvico F., Como C., Colombo G., Zani F., Buttini F., Bettini R., Rossi
A., Colombo P.
Lecithin/chitosan controlled release nanopreparations of tamoxifen citrate: Loading, enzyme-trigger release and cell uptake.
J Control Release 167(3), 276-283 (2013)
doi: 10.1016/j.jconrel.2013.02.009

40) Losi E., Peppas N.A., Ketcham R.A., Colombo G., Bettini R., Sonvico F., Colombo P.
Investigation of the swelling behavior of Dome Matrix drug delivery modules by high -resolution X-ray computed tomography.
J Drug Del Sci Tech 23(2), 165-170 (2013)
doi: 10.1016/S0376-8716(00)90000-0

41) Balducci A.G., Magosso E., Colombo G., Sonvico F., Khan N.A., Yuen K.H., Bettini R., Colombo P., Rossi A.
Agglomerated oral dosage forms of artemisinin/β-cyclodextrin spray-dried primary microparticles showing increased dissolution rate and bioavailability.
AAPS PharmSciTech 14(3), 911-918 (2013)
doi: 10.1208/s12249-013-9982-9.

42) Di Bari M.T., Padula C., Santi P., Sonvico F., Barbieri S., Chiapponi C., Ollivier J., Deriu A.
Dynamics of Water and Small Molecules in Bioadhesive Polymer Films
J. Phys. Soc. Jpn. 82 (2013) SA021 (8 pages).

43) Cortie MB, Nafea EH, Chen H, Valenzuela SM, Ting SS, Sonvico F, Milthorpe B.
Nanomedical research in Australia and New Zealand.
Nanomedicine (Lond) 8(12) (2013)1999-2006.
doi: 10.2217/nnm.13.179.

2014

44) Balducci A.G., Cagnani S., Sonvico F., Rossi A., Barata P., Colombo G., Colombo P., Buttini F.
Pure insulin highly respirable powders for inhalation.
Eur J Pharm Sci 51 (2014) 110-117.
doi:10.1016/j.ejps.2013.08.009.

45) Garrastazu G., Stanisçuaki Guterres S., Balducci A.G., Colombo P., Sonvico F.
Polymeric films loaded with vitamin E and Aloe vera for topical application in the treatment of Burn Wounds
BioMed Res Int 2014 (2014), Article ID 641590, 9 pages
doi:10.1155/2014/641590

46) Romana B., Batger M., Prestidge C.A., Colombo G., Sonvico F.
 Expanding the therapeutic potential of statins by means of nanotechnology enabled drug delivery systems
Curr Topics Med Chem 14 (2014) 1182-1193.

2015

47) Rotoli B.M., Gatti R., Movia D., Bianchi M.G., Di Cristo L., Fenoglio I., Sonvico F., Bergamaschi E., Prina-Mello, A., Bussolati O.
Identifying contact-mediated, localized toxic effects of MWCNT aggregates on epithelial monolayers: a single-cell monitoring toxicity assay
Nanotoxicology 29 (2015) 1-12.
doi:10.3109/17435390.2014.918203

48) Sonvico F., Coleman V., Traini D., Young P.M.
Evolved gas analysis during thermal degradation of salbutamol sulphate.
J Therm Anal Calorim 120(1) (2015) 789-794
doi: 10.1007/s10973-014-3935-8

49) Comfort C., Garrastazu G., Pozzoli M., Sonvico F.
Opportunities and Challenges for the Nasal Administration of Nanoemulsions.
Curr Topics Med Chem 15 (4) (2015) 356-368.

50) Pescina S., Sonvico F., Santi P., Nicoli S.
Therapeutics and Carriers: The Dual Role of Proteins in Nanoparticles for Ocular Delivery.
Curr Topics Med Chem 15 (4) (2015) 369-385.

51) Raphael AP, Garrastazu G, Sonvico F, Prow TW.
Formulation design for topical drug and nanoparticle treatment of skin disease.
Ther Deliv 6(2) (2015) 197-216.
doi: 10.4155/tde.14.106

52) Martinelli F, Balducci AG, Rossi A, Sonvico F, Colombo P, Buttini F.
“Pierce and inhale” design in capsule based dry powder inhalers: effect of capsule piercing and motion on aerodynamic performance of drugs.
Int J Pharm 487(1-2) (2015) 197-204.
doi:10.1016/j.ijpharm.2015.04.003

53) Balducci AG, Steckel H, Guarneri F, Rossi A, Colombo G, Sonvico F, Cordts E, Bettini R, Colombo P, Buttini F
High shear mixing of lactose and salmeterol xinafoate dry powder blends: biopharmaceutic and aerodynamic performances
J Drug Deliv Sci Technol, 30 (2015) 443-449
dos: 10.1016/j.jddst.2015.07.010

54) Barbieri S, Buttini F, Rossi A, Bettini R, Colombo P, Ponchel G, Sonvico F,
Colombo G.
Ex vivo permeation of tamoxifen and its 4-OH metabolite through rat
intestine from lecithin/chitosan nanoparticles.
Int J Pharm, 491(1-2) (2015) 99-104
doi: 10.1016/j.ijpharm.2015.06.021

2016

55) Balducci AG, Magosso E, Colombo G, Sonvico F.
From tablets to pharmaceutical nanotechnologies: Innovation in drug delivery strategies for the administration of antimalarial drugs.
J Drug Deliv Sci Technol, 32, Part B (2016) 167-173
doi: 10.1016/j.jddst.2015.06.003

56) Pereira GG, Detoni CB, Balducci AG, Rondelli V, Colombo P, Guterres SS, Sonvico F.
Hyaluronate nanoparticles included in polymer films for the prolonged release of vitamin E for the management of skin wounds.
Eur J Pharm Sci, 83 (2016) 233-211.
doi:10.1016/j.ejps.2016.01.002

57) Garrastazu Pereira G, Lawson AJ, Buttini F, Sonvico F.
Loco-regional administration of nanomedicines for the treatment of lung cancer.
Drug Deliv, 23(8) (2016) 2881-2896
doi:10.3109/10717544.2015.1114047

58) Buttini F, Rossi I, Di Cuia M, Rossi A, Colombo G, Elviri L, Sonvico F, Balducci AG. Combinations of colistin solutions and nebulisers for lung infection management in cystic fibrosis patients.
Int J Pharm, 502 (1-2) (2016) 242-248.
doi: 10.1016/j.ijpharm.2016.02.005

59) Pozzoli M, Rogueda P, Zhu B, Smith T, Young PM, Traini D, Sonvico F.
Dry powder nasal drug delivery: challenges, opportunities and a study of the
commercial Teijin Puvlizer Rhinocort device and formulation.
Drug Dev Ind Pharm, 42(10) (2016) 1660-8.
doi: 10.3109/03639045.2016.1160110.

60) Pozzoli M, Ong HX, Morgan L, Sukkar M, Traini D, Young PM, Sonvico F. Application of RPMI 2650 nasal cell model to a 3D printed apparatus for the
testing of drug deposition and permeation of nasal products.
Eur J Pharm Biopharm, 107 (2016) 223-33.
doi: 10.1016/j.ejpb.2016.07.010.

61) Colombo G, Bortolotti F, Chiapponi V, Buttini F, Sonvico F, Invernizzi R, Qualglia F, Danesino C, Pagella F, Russo P, Bettini R, Colombo P, Rossi A
Nasal powders of thalidomide for local treatment of nose bleeding in persons affected by hereditary hemorrhagic telangiectasia.
Int J Pharm, 514 (1) (2016) 229-237
doi:10.1016/j.ijpharm.2016.07.002.

62) Clementino A, Batger M, Garrastazu G, Pozzoli M, Del Favero E, Rondelli V, Gutfilen B, Barboza T, Sukkar MB, Souza SAL, Cantù L, Sonvico F
The nasal delivery of nanoencapsulated statins - an approach for brain delivery.
Int J Nanomed, 11 (2016) 6575-6590
doi:10.2147/IJN.S119033

2017

63) Şenyiğit T, Sonvico F, Rossi A, Tekmen I, Santi P, Colombo P, Nicoli S, Özer
Ö.
In Vivo Assessment of Clobetasol Propionate-Loaded Lecithin-Chitosan
Nanoparticles for Skin Delivery.
Int J Mol Sci, 18(1) (2017) E32.
doi:10.3390/ijms18010032.

64) Martinelli F, Balducci AG, Kumar A, Sonvico F, Forbes B, Bettini R, Buttini F.
Engineered sodium hyaluronate respirable dry powders for pulmonary drug delivery.
Int J Pharm, 517(1-2) (2017) 286-295.
doi: 10.1016/j.ijpharm.2016.12.002.

65) Pozzoli M, Traini D, Young PM, Sukkar MB, Sonvico F.
Development of a Soluplus budesonide freeze-dried powder for nasal drug delivery. Drug Dev Ind Pharm, 43(9) (2017) 1510-1518.
doi: 10.1080/03639045.2017.1321659.

66) Sonvico F, Zimetti F, Pohlmann AR, Guterres SS.
Drug delivery to the brain: how can nanoencapsulated statins be used in the clinic?
Ther Deliv, 8(8) (2017) 625-631.
doi: 10.4155/tde-2017-0044.

67) Sonvico F, Conti C, Colombo G, Buttini F, Colombo P, Bettini R, Barchielli M,
Leoni B, Loprete L, Rossi A.
Multi-kinetics and site-specific release of gabapentin and flurbiprofen from oral fixed-dose combination: in vitro release and in vivo food effect.
J Control Release, 262 (2017) 296-304.
doi: 10.1016/j.jconrel.2017.07.042.

68) Telò I, Favero ED, Cantù L, Frattini N, Pescina S, Padula C, Santi P, Sonvico
F, Nicoli S.
Gel-like TPGS-Based Microemulsions for Imiquimod Dermal Delivery:
Role of Mesostructure on the Uptake and Distribution into the Skin.
Mol Pharm. 14 (10), (2017) 3281–3289.
doi: 10.1021/acs.molpharmaceut.7b00348.

2018

69) Giuliani A, Balducci AG, Zironi E, Colombo G, Bortolotti F, Lorenzini L,
Galligioni V, Pagliuca G, Scagliarini A, Calzà L, Sonvico F.
In vivo nose-to-brain delivery of the hydrophilic antiviral ribavirin by microparticle
agglomerates.
Drug Deliv. 25(1) (2018) 376-387.

70) Sonvico F, Barbieri S, Colombo P, Mucchino, C, Barocelli E, Cantoni AM, Cavazzoni A, Petronini PG, Rusca M, Carbognani P, Ampollini L.
Physicochemical and pharmacokinetic properties of polymeric films loaded with cisplatin for the treatment of malignant pleural mesothelioma
J Thor Disease, 10 (2018) S194-S206.
doi: 10.21037/jtd.2017.10.12

71) Ampollini L, Barocelli E, Cavazzoni A, Petronini P, Mucchino C, Cantoni AM, Leonardi F, Ventura L, Barbieri S, Colombo P, Fusari A, Carbognani P, Rusca M, Sonvico F.
Polymeric films loaded with cisplatin for malignant pleural mesothelioma: A pharmacokinetic study in an ovine model
J Thor Disease, 10 (2018) S207-S220.
doi: 10.21037/jtd.2017.10.74

72) Tiozzo Fasiolo L, Manniello MD, Tratta E, Buttini F, Rossi A, Sonvico F, Bortolotti F, Russo P, Colombo G.
Opportunity and challenges of nasal powders: Drug formulation and delivery.
Eur J Pharm Sci, 113 (2018) 2-17
doi: 10.1016/j.ejps.2017.09.027

73) Rossi I, Sonvico F, McConville JT, Rossi F, Fröhlich E, Zellnitz S, Rossi A, Del Favero E, Bettini R, Buttini F.
Nebulized coenzyme Q10 nanosuspensions: A versatile approach for pulmonary antioxidant therapy
Eur J Pharm Sci, 113 (2018) 159-170
doi: 10.1016/j.ejps.2017.10.024

EDITORE DI LIBRO DIDATTICO

PRINCIPI DI CALCOLO FARMACEUTICO (autori: H. Ansel, S. Stockton)
A cura di: Gaia Colombo, Alessandra Rossi, Paola Russo, Fabio Sonvico
Casa Editrice: EDRA
ISBN: 978-88-214-4394-7

CAPITOLI DI LIBRI

I. Colombo P., Sonvico F
Les formes pharmaceutiques du futur
in Histoire de la Pharmacie Galénique, Preat V., Roland-Marcelle N. and Van den Abeele B. Editors; UCL Presses Universitaires de Louvain - Louvain-la-Neuve, 279-299 (2006) ISBN: 2-87463-049-7
II. Colombo P., Cagnani S., Sonvico F., Santi P., Russo P., Colombo G.
Biological in vitro models for absorption by nonoral routes
Chapter 5.12 in Comprehensive Medicinal Chemistry 2nd Edition, Taylor J.B. and Triggle D.J. Editors-in-Chief; Volume 5, ADME-Tox Approaches, Testa B. and van de Waterbeemd H. Volume Editors; Elsevier - Oxford, 279-299 (2007) ISBN: 978-0-08-044513-7

III. Colombo P., Santi P., Siepmann J., Colombo G., Sonvico F., Rossi A., Strusi O.L.
Swellable and rigid matrices: controlled release matrices with cellulose ethers
in Pharmaceutical Dosage Forms: Tablets, Edited by Augsburger L.L. and Hoag S.W.; Informa Healthcare - New York, 433-468 (2008) ISBN: 978-0-8493-9015-9

IV. Salmaso S., Sonvico F.
Targeted cyclodextrins
in Cyclodextrins in Pharmaceutics, Cosmetics, and Biomedicine: Current and Future Industrial Applications, Edited by Bilensoy E.; Wiley - Hoboken, 251-274 (2011) ISBN: 978-0-470-47422-8

V. Colombo P., Sonvico F., Buttini F.
Nanostructures overcoming the pulmonary barrier: drug delivery strategies
in Nanostructured Biomaterials for Overcoming Biological Barriers, Edited by Alonso M.J. and Csaba N.S.; RSC Publishing, 273-300 (2012) ISBN: 978-1-84973-378-6

VI. Barbieri S., Sonvico F., Bouchemal K., Ponchel G., Colombo P.
Tamoxifen loaded auto-assembled nanoparticles for oral delivery: cytotoxicity and permeability studies
in NanoFormulation, Edited by Tiddy G.J.T. and Tan R.B.H.; RSC Publishing, Cambridge (UK), pp. 70-76 (2012) ISBN: 978-1-84973-378-6
International Conference on Materials for Advanced Technologies - ICMAT 2011, Singapore, 26 June - 1 July 2011

VII. Colombo B.M., Morlacchi I., Sonvico F.
Pharmaceutical packaging: Materials and Types (Italian)
in Principi di Tecnologia Farmaceutica, Edited by Colombo P., Alhaique F., Caramella C., Conti B., Gazzaniga A., Vidale E.; Casa Editrice Ambrosiana, \ Rozzano (Italy), pp. 161-172 (2015) ISBN: 978-8808-18672-0

BREVETTI

Colombo P., Santi P., Bettini R., Strusi O.L., Sonvico F., Colombo G.
New modules, new assemblage kits and new assemblies for the controlled release of substances
PCT/EP2006/011661, filing date 05/12/2006

Raffin R., Colombo P., Sonvico F., Colombo G., Rossi A., Buttini F.
Compositions in powder form made of soft agglomerates of a micronized drug and of a two-components excipient, and process for their prearation
PCT/EP2007/061599, filing date 26/10/2007

Colombo G., Colombo P., Gallina L., Sonvico F., Scagliarini A.
Sprayable pharmaceutical compositions comprising sucralfate gel for treating skin or mucosa lesions
PCT/EP2008/064528, filing date 27/10/2008

Colombo G., Colombo P., Gallina L., Scagliarini A., Sonvico F.
Sprayable pharmaceutical compositions for topical application comprising sucralfate gel
MI2010A002366, EP2654813 A1, publication date 30/10/2013, granted 11/02/2016

Rossi A., Colombo P., Sonvico F., Barchielli M.
Multilayered pharmaceutical formulation.
WO 2014/013006, publication date 23/01/2014